Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Pulmonary infiltrates



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(per page)
PMID (PMCID)
10579281
 MALE
Nitric oxide successfully used to treat acute chest syndrome of sickle cell disease in a young adolescent.
Sullivan KJ, Goodwin SR, Evangelist J, Moore RD, Mehta P.
Crit Care Med. 1999;27(11):2563-8.
A 15-yr-old black male with sickle cell disease, bilateral pulmonary infiltrates, refractory hypoxemia, and unstable hemodynamics.
8907818
 FEMALE Adult
Sarcoidosis presenting with prolonged fever in a patient with sickle cell anemia.
Chan ED, Terada LS, Schwarz MI.
J Natl Med Assoc. 1995;87(11):826-8.
A patient with sickle cell anemia presented with fever and pulmonary infiltrates of several weeks duration that were unresponsive to antibiotics.
2554726
 MALE Adult
Alveolar cell carcinoma complicating sickle cell anemia: a chance occurrence?
Labi M, Haponik EF, Welsh RA, Summer WR.
Am J Hematol. 1989;32(3):222-5.
As survival increases in individuals with sickle cell disease, alveolar cell carcinoma must be considered in these differential diagnosis of otherwise unexplained chronic pulmonary infiltrates.
7268869
 MALE
Exchange red blood cell pheresis in a pediatric patient with severe complications of sickle cell anemia.
Kleinman S, Thompson-Breton R, Breen D, Hurvitz C, Goldfinger D.
Transfusion. 1981;21(4):443-6.
This procedure was used in a 13-year-old male with sickle cell anemia, who presented with bilateral pulmonary infiltrates, respiratory distress, and hypoxemia, unresponsive to antibiotics and other means of conservative therapy.