Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Ischemic stroke



Total: 4

                       


(per page)
PMID (PMCID)
29953035
 FEMALE
Nonaneurysmal Subarachnoid Hemorrhage in Sickle Cell Disease: Description of a Case and a Review of the Literature.
Zuccoli G, Nardone R, Rajan D, Khan AS, Cummings DD.
Neurologist. 2018;23(4):122-127.
Descriptions of the natural history of cerebrovascular complications of sickle cell disease (SCD) characterize ischemic stroke as common during childhood and hemorrhagic stroke as more common in adulthood.
19066384
(2756016)
 FEMALE Adult
Evolution of novel small-molecule therapeutics targeting sickle cell vasculopathy.
Kato GJ, Gladwin MT.
JAMA. 2008;300(22):2638-46.
A 34-year-old African American woman with sickle cell disease and history of relatively severe hemolysis, chronic leg ulcers, and mild pulmonary hypertension presented with a new ischemic stroke.
8442641
 MALE
[Ischemic cerebrovascular accidents in homozygous sickle cell anemia. Two case reports].
Mbonda E, Thuret I, Pinsard N.
Ann Pediatr (Paris). 1993;40(1):23-7.
Two cases of ischemic stroke in children of Tunisian descent with sickle cell anemia are reported.
2134744
 MALE
Salmonella osteomyelitis with epidural abscess. A case report with review of osteomyelitis in children with sickle cell anemia.
Martino AM, Winfield JA.
Pediatr Neurosurg. 1990;16(6):321-5.
Neurologic complications of sickle cell anemia are most commonly ischemic strokes secondary to sludging in cerebral arterioles.