Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Headache

Cephalgia, or pain sensed in various parts of the head, not confined to the area of distribution of any nerve.


Total: 23

                       


(per page)
PMID (PMCID)
30500454
 MALE
T2-blackout effect on DWI as a sign of early bone infarct and sequestration in a patient with sickle cell disease.
Tuna IS, Tarhan B, Escobar M, Albayram MS.
Clin Imaging. 2019;54:15-20.
We present a case of an 18-year-old male with a history of sickle cell disease, who was transferred to our emergency department with progressively severe headache and jaw pain for one-week.
30626228
 FEMALE Young Adult
Successful Outcome of Hyperhemolysis in Sickle Cell Disease following Multiple Lines of Treatment: The Role of Complement Inhibition.
Vlachaki E, Gavriilaki E, Kafantari K, Adamidou D, Tsitsikas D, Chasapopoulou E, Anagnostopoulos A, Tsapas A.
Hemoglobin. 2018;42(5-6):339-341.
A 21-year old female sickle cell disease patient [Hb S (HBB: c.20A>T)/946-thalassemia (946-thal)] presented at our Adult Thalassaemia Unit, Hippokration General Hospital of Thessaloniki, Thessaloniki, Greece, with headaches, perioral numbness and pain in both antibrachia.
24232306
 MALE Adult
Ketamine infusion for sickle cell pain crisis refractory to opioids: a case report and review of literature.
Uprety D, Baber A, Foy M.
Ann Hematol. 2014;93(5):769-71.
A 31-year-old African-American male with history of sickle cell disease presented to the emergency department with complaints of chest tightness, multiple joint pain, and headache for 1 week.
24447643
 FEMALE Young Adult
Non-traumatic spontaneous acute epidural hematoma in a patient with sickle cell disease.
Serarslan Y, Aras M, Altas M, Kaya H, Urfal B.
Neurocirugia (Astur). 2014;25(3):128-31.
A 19-year-old female with sickle cell anemia (SCD) was referred to our hospital after two days of hospitalization at another hospital for a headache crisis.
23206496
 MALE
Radiographic features in a rare case of sphenoid sinus extramedullary hematopoeisis in sickle cell disease.
Sklar M, Rotaru C, Grynspan D, Bromwich M.
Int J Pediatr Otorhinolaryngol. 2013;77(2):294-7.
Here, we present a case of a young boy with known sickle cell disease who presented to hospital with headaches of new onset.
23831252
 FEMALE
Reversible posterior leukoencephalopathy syndrome after blood transfusion in a pediatric patient with sickle cell disease.
Kolovou V, Zampakis P, Ginopoulou A, Varvarigou A, Kaleyias J.
Pediatr Neurol. 2013;49(3):213-7.
We report a 13-year-old female with sickle cell disease presenting with a headache and two isolated episodes of partial seizures with secondary generalization after blood transfusion.
21657139
 MALE Adult
Homozygous sickle cell anemia and secondary complications: a case study.
Yontz CJ, Waller KV.
Clin Lab Sci. 2011;24(2):78-84.
A 26-year-old African-American male presented with chest and back pain, fatigue and a history of the following: homozygous sickle cell anemia, pain crises, stroke, hip replacement following avascular necrosis of the femoral head, priapism, chronic transfusions, iron overload, hypertension, migraine headaches, port infections, depression and type II diabetes.
21803935
 MALE Young Adult
Severe unilateral headache caused by skull bone infarction with epidural haematoma in a patient with sickle cell disease.
Arends S, Coebergh JA, Kerkhoffs JL, van Gils A, Koppen H.
Cephalalgia. 2011;31(12):1325-8.
Severe unilateral headache caused by skull bone infarction with epidural haematoma in a patient with sickle cell disease.
19589461
(2740936)
 FEMALE Child
Stroke in sickle cell anemia: alternative etiologies.
Dowling MM, Quinn CT, Rogers ZR, Journeycake JM.
Pediatr Neurol. 2009;41(2):124-6.
An 11-year-old girl with sickle cell anemia presented with severe headache and was found to have recurrent bilateral multifocal strokes in a cardioembolic pattern.
19250591
 FEMALE Adult
Unusual clivus lesion demonstrating extramedullary haematopoiesis: case report.
Kulendra K, Butler C, Grant W, Sandison A, Cho G, Patel MC.
J Laryngol Otol. 2009;123(5):e15.
An unusual clivus mass is reported, following investigation of memory disturbance and headaches in a patient with beta thalassaemia and sickle cell disease.
20847926
(2940258)
 OTHER
Woman with Sickle Cell Disease with Current Sigmoid Sinus Thrombosis and History of Inadequate Warfarin Use during a Past Thrombotic Event.
Celikbilek A, Celikbilek M, Bozkurt A, Karakurum Goksel B, Tan M, Ozdogu H.
Case Rep Neurol. 2009;1(1):15-19.
We report a 20-year-old woman with sickle cell disease (SCD) who presented with a severe pulsating headache, nausea, and vomiting.
18520831
 MIXED_SAMPLE Child
Orbital compression syndrome in sickle cell disease.
Sokol JA, Baron E, Lantos G, Kazim M.
Ophthalmic Plast Reconstr Surg. 2008;24(3):181-4.
This diagnosis should be considered when a patient with sickle cell disease presents with headache, proptosis, decreased motility, and/or optic nerve compromise.
14525820
 FEMALE Adult
Postdural puncture headache in a parturient with sickle cell disease: use of an epidural colloid patch.
Chiron B, Laffon M, Ferrandiere M, Pittet JF.
Can J Anaesth. 2003;50(8):812-4.
Postdural puncture headache in a parturient with sickle cell disease: use of an epidural colloid patch.
9331199
 MALE Child
Orbital compression syndrome in sickle cell disease.
Curran EL, Fleming JC, Rice K, Wang WC.
Ophthalmology. 1997;104(10):1610-5.
The literature contains 11 reports of 16 young patients with sickle cell disease (15 sickle cell disease [Hb SS] and 1 hemoglobin sickle cell disease [Hb SC]) with rapidly developing findings ranging from frontal headache, fever, and eyelid edema to bilateral complete orbital compression syndrome.
9331199
 MALE Child
Orbital compression syndrome in sickle cell disease.
Curran EL, Fleming JC, Rice K, Wang WC.
Ophthalmology. 1997;104(10):1610-5.
Orbital complications in sickle cell disease are unusual manifestations in which a vaso-occlusive process in the marrow space around the orbit results in frontal headache, fever, eyelid edema, and often orbital compression syndrome.
9331199
 MALE Child
Orbital compression syndrome in sickle cell disease.
Curran EL, Fleming JC, Rice K, Wang WC.
Ophthalmology. 1997;104(10):1610-5.
The literature contains 11 reports of 16 young patients with sickle cell disease (15 sickle cell disease [Hb SS] and 1 hemoglobin sickle cell disease [Hb SC]) with rapidly developing findings ranging from frontal headache, fever, and eyelid edema to bilateral complete orbital compression syndrome.
9331199
 MALE Child
Orbital compression syndrome in sickle cell disease.
Curran EL, Fleming JC, Rice K, Wang WC.
Ophthalmology. 1997;104(10):1610-5.
The literature contains 11 reports of 16 young patients with sickle cell disease (15 sickle cell disease [Hb SS] and 1 hemoglobin sickle cell disease [Hb SC]) with rapidly developing findings ranging from frontal headache, fever, and eyelid edema to bilateral complete orbital compression syndrome.
8862847
 MALE Adult
Headache and scalp edema in sickle cell disease.
Pari G, Schipper HM.
Can J Neurol Sci. 1996;23(3):224-6.
We describe the case of a 25-year-old man with sickle cell disease who developed a severe headache of acute onset, located at the vertex.
8862847
 MALE Adult
Headache and scalp edema in sickle cell disease.
Pari G, Schipper HM.
Can J Neurol Sci. 1996;23(3):224-6.
Headache and scalp edema in sickle cell disease.
8862847
 MALE Adult
Headache and scalp edema in sickle cell disease.
Pari G, Schipper HM.
Can J Neurol Sci. 1996;23(3):224-6.
In addition to the more common intracranail vaso-occlusive complications, skull infarction should be considered as a cause of newonset headache in patients with sickle cell disease, especially if scalp edema is present.