Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Leukoencephalopathy

This term describes abnormality of the white matter of the cerebrum resulting from damage to the myelin sheaths of nerve cells.


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PMID (PMCID)
24656986
 FEMALE Adult
Sickle cell disease and posterior reversible leukoencephalopathy.
Geevasinga N, Cole C, Herkes GK, Barnett Y, Lin J, Needham M.
J Clin Neurosci. 2014;21(8):1329-32.
Only a few patients with the association between sickle cell disease and posterior reversible leukoencephalopathy have been described in the adult literature.