Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Atherosclerosis

A condition characterized by patchy atheromas or atherosclerotic plaques which develop in the walls of medium-sized and large arteries and can lead to arterial stenosis with reduced or blocked blood flow.


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(per page)
PMID (PMCID)
3381795
 MALE Adult
Massive nonatherosclerotic myocardial infarction in sickle cell anemia.
McCormick WF.
Am J Forensic Med Pathol. 1988;9(2):151-4.
Myocardial infarction, unassociated with atherosclerosis, has very rarely been reported in sickle cell anemia.
6230006
 MIXED_SAMPLE Infant
Myocardial infarction in sickle cell anemia.
Barrett O Jr, Saunders DE Jr, McFarland DE, Humphries JO.
Am J Hematol. 1984;16(2):139-47.
Literature reports of postmortem examinations on patients with sickle cell anemia confirm the scarcity of coronary atherosclerosis and myocardial infarction in these patients.
403890
 MALE Adult
[Myocardial infarction and heterozygous sickle cell anemia. Apropos of 2 cases].
Botreau-Roussel P, Drobinski G, Levy R, Vachon JM, Nivet M, Grosgogeat Y.
Arch Mal Coeur Vaiss. 1977;70(2):141-7.
The authors report two cases of myocardial infarction in patients whose coronary arteries were relatively free from atherosclerosis; they were young men, with the heterozygous form of sickle cell disease AS.