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Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Osteolysis

Osteolysis refers to the destruction of bone through bone resorption with removal or loss of calcium.

Total: 1

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PMID (PMCID)
8710044	MIXED_SAMPLE	Adult
	Vertebral bone destruction in sickle cell disease: infection, infarction or both.
	Kooy A, de Heide LJ, ten Tije AJ, Mulder AH, Tanghe HL, Kluytmans JA, Michiels JJ. Neth J Med. 1996;48(6):227-31.
	Infectious and vaso-occlusive vertebral bone and joint destruction in two patients with sickle cell disease (SCD) are featured by H-shaped vertebrae, kyphotic angulation, osteolysis of endplates and collapse of intervertebral discs as shown by X-ray films and magnetic resonance imaging.