Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Autoimmunity

The occurrence of an immune reaction against the organism's own cells or tissues.


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PMID (PMCID)
6803409
 MALE Child
A mimicking red blood cell autoantibody accompanying transfusion and alloimmunization.
Wenz B, Gurtlinger K, Wheaton D, Dugan EP.
Transfusion. 1982;22(2):147-50.
A patient with sickle cell disease who concomitantly developed red cell autoimmunity and alloimmunization is reported.