Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Spherocytosis

The presence of erythrocytes that are sphere-shaped.


Total: 4

                       


(per page)
PMID (PMCID)
16841583
 MIXED_SAMPLE Infant
[Anaemia in adopted children, not always iron deficiency].
Veneman NG, Waalkens HJ, Tamminga RY.
Ned Tijdschr Geneeskd. 2006;150(25):1369-72.
An incorrect diagnosis of iron deficiency may result in ongoing and unjustified iron supplementation leading to harmful iron accumulation in thalassaemia and a delay in the correct treatment in sickle cell anemia or spherocytosis which could carry considerable risk.
10461646
 FEMALE Middle Aged
Hydroxyurea-induced leg ulcers: is macroerythrocytosis a pathogenic factor?
Velez A, Garcia-Aranda JM, Moreno JC.
J Eur Acad Dermatol Venereol. 1999;12(3):243-4.
Macroerythrocytosis can be considered as an 'acquired' blood dyscrasia, and similar leg ulcers have long been known to occur with certain hereditary blood dyscrasias, such as sickle cell anemia, thalasemia, and spherocytosis.
2621101
 MIXED_SAMPLE Adult
Asymptomatic intrathoracic extramedullary hematopoiesis: a report of three cases.
Murakami T, Dixon AC, Ho RC, Nakamura JM.
Hawaii Med J. 1989;48(10):430-2, 434-6.
The hemoglobinopathies (such as thalassemia, spherocytosis, and sickle cell disease), neoplastic diseases such as leukemia and lymphoma, and others, including myelofibrosis and osteitis fibrosa cystica, are associated with EMH.
3021015
 MALE
Human parvovirus-associated red cell aplasia in the absence of underlying hemolytic anemia.
Van Horn DK, Mortimer PP, Young N, Hanson GR.
Am J Pediatr Hematol Oncol. 1986;8(3):235-9.
Human parvovirus (HPV) infection has recently been implicated as the cause of aplastic crisis in patients with hemolytic anemias such as congenital spherocytosis and sickle cell anemia.