Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Chronic hemolytic anemia

An chronic form of hemolytic anemia.


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PMID (PMCID)
29261629
 MALE
False-Positive Heat-Damaged RBC Scan for Splenosis: Case of Retroperitoneal Extramedullary Hematopoiesis.
Donald JS, Chen DL, Peterson J, Perry M.
Clin Nucl Med. 2018;43(2):139-140.
Extramedullary hematopoiesis (EMH) is a well-known compensatory response to severe anemia, most commonly due to a chronic hemolytic anemia such as thalassemia or sickle cell disease.
24960379
 FEMALE
Facial swelling in a sickle cell patient.
DeBlieux TK, Jackson N, Jeyakumar A, Townsend JA, Naik BV.
Pediatr Dent. 2014;36(3):104-6.
Sickle cell disease (SCD) is characterized as a chronic hemolytic anemia with vaso-occlusive crises that result in multisystem organ damage.
26405395
 OTHER
Interaction of - alpha 3.7, ss Thalassemia Mutation IVS 1-5 and HbD Punjab in a Family: A Case Report.
Pandey S, Ranjan R, Mishra RM, Pandey S, Saxena R.
Indian J Clin Biochem. 2012;27(3):314-7.
HbD trait and HbD homozygous generally asymptomatic condition but when HbD co-inherit with thalassemia and sickle cell anemia, produces clinically significant conditions like chronic hemolytic anemia.
12827657
 MIXED_SAMPLE Adult
Acute pancreatitis during sickle cell vaso-occlusive painful crisis.
Ahmed S, Siddiqui AK, Siddiqui RK, Kimpo M, Russo L, Mattana J.
Am J Hematol. 2003;73(3):190-3.
Sickle cell disease is characterized by chronic hemolytic anemia and vaso-occlusive painful crisis.
1521400
 FEMALE Adult
Sickle-cell anemia: a case report and literature review.
Cherry-Peppers G, Davis V, Atkinson JC.
Clin Prev Dent. 1992;14(4):5-9.
Sickle-cell disease is characterized by the pathophysiological features of chronic hemolytic anemia, vaso-occlusion resulting in ischemic tissue injury and painful episodes.
2619135
 FEMALE Child
[Sickle cell anemia in 2 Spanish white girls].
Merino Alonso de Ozalla R, Gonzalez Iglesias MJ, Alberto Alonso MJ, Romero Vazquez-Gulias D, Fernandez Ranada JM.
An Esp Pediatr. 1989;31(5):470-2.
The investigation of a chronic hemolytic anemia in a white girl reveals the presence of Hb SS (sickle cell anemia in its classic form), that carries out the same unsuspected diagnosis in her sister and the realization of both parents as carriers of the sickle cell anemia trait.
2619135
 FEMALE Child
[Sickle cell anemia in 2 Spanish white girls].
Merino Alonso de Ozalla R, Gonzalez Iglesias MJ, Alberto Alonso MJ, Romero Vazquez-Gulias D, Fernandez Ranada JM.
An Esp Pediatr. 1989;31(5):470-2.
The investigation of a chronic hemolytic anemia in a white girl reveals the presence of Hb SS (sickle cell anemia in its classic form), that carries out the same unsuspected diagnosis in her sister and the realization of both parents as carriers of the sickle cell anemia trait.
647121
 MALE
Failure of the alpha-thalassemia gene to decrease the severity of sickle cell anemia.
Natta C.
Blood. 1978;51(6):1163-8.
A 15-yr-old black male with homozygous sickle cell disease was severely growth retarded and had a chronic hemolytic anemia requiring transfusions.
265481
 MIXED_SAMPLE Child
Differential diagnosis of some simple osseous lesions associated with sickle-cell anemia.
Sanger RG, Greer RO Jr, Averbach RE.
Oral Surg Oral Med Oral Pathol. 1977;43(4):538-45.
Sickle-cell disease is characterized by chronic hemolytic anemia, rapid destruction of defective erythrocytes, with consequent circulatory disturbances.