Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Pigment gallstones

Gallstones composed primarily of bilirubin and calcium salts (calcium bilirubinate) with a low cholesterol concentration.


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PMID (PMCID)
19075544
 MALE Adult
Multiple primary choledocholithiasis in sickle cell disease.
Vicari P, Gil MV, Cavalheiro Rde C, Figueiredo MS.
Intern Med. 2008;47(24):2169-70.
Although patients with sickle cell disease (SCD) are at high risk of development of pigmented gallstones due to chronic hemolysis, primary choledocholithiasis in SCD is very uncommon.