Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Severe infection

A type of infection that is regarded as a sign of a pathological susceptibility to infection because of unusual severity or intensity of the infection.


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PMID (PMCID)
23340961
 FEMALE Child
Sickle cell disease with double stroke in a Moroccan family.
Hamzi K, Itto AB, Jouhadi Z, Slassi I, Nadifi S.
J Mol Neurosci. 2013;50(2):311-3.
The sickle-cell disease is a group of chronic hemolytic diseases which associates three types of injuries: severe anemia, severe infections, and ischemic vaso-occlusive crisis that are secondary to conflicts between small vessels and red blood cells too deformable.
9155683
 FEMALE Adult
Bone marrow necrosis in antiphospholipid syndrome.
Paydas S, Kocak R, Zorludemir S, Baslamisli F.
J Clin Pathol. 1997;50(3):261-2.
It is most commonly found in patients with neoplastic disorders, severe infections and sickle cell anemia.
1987922
 FEMALE Middle Aged
Bone marrow necrosis in leukemic-phase follicular lymphoma.
Mehta K, Pawel BR, Gadol C.
Arch Pathol Lab Med. 1991;115(1):89-92.
It is most commonly found in patients with neoplastic disorders, severe infections, and sickle cell anemia.
6660041
 MALE Middle Aged
Bone marrow necrosis. Report of a case and a brief review of the literature.
Hansen PV, Andersen J, Mygind H.
Acta Med Scand. 1983;214(4):331-6.
It is most commonly found in patients with neoplastic disorders, severe infections and sickle cell disease.