Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Sarcoma

A connective tissue neoplasm formed by proliferation of mesodermal cells. Bone and soft tissue sarcomas are the main types of sarcoma. Sarcoma is usually highly malignant.

Total: 1

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PMID (PMCID)
188537	MALE	Adult
	Malignant (fibrous) histiocytoma arising in association with a bone infarct in sicle-cell disease: coincidence or cause-and-effect?
	Mirra JM, Gold RH, Marafiote R. Cancer. 1977;39(1):186-94.
	This is the ninth reported case of human sarcoma associated with bone infarct and the first associated with sickle-cell disease.