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Sickle cell anemia

Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur.

Scarring

Total: 1

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PMID (PMCID)
1772123	MALE	Adult
	Case report: splenic infarction and acute splenic sequestration in adults with hemoglobin SC disease.
	Orringer EP, Fowler VG Jr, Owens CM, Johnson AE, Mauro MA, Dalldorf FG, Croom RD. Am J Med Sci. 1991;302(6):374-9.
	While acute splenic sequestration and splenic infarction are commonly observed in infants and young children with sickle cell anemia, they are rarely experienced by adult hemoglobin S homozygotes because the recurrent splenic infarction that takes place during childhood is typically followed by scarring, atrophy, and splenic fibrosis.