Kawasaki disease

Kawasaki disease (KD) is a febrile, systemic, self-limiting vasculitis affecting children and characterized by inflammation in the medium sized vessels associated with coronary arterial aneurysms (CAA) that may be life threatening when untreated. KD is the most common cause of acquired heart disease in children in developed countries and is a risk factor for ischemic heart disease in adulthood.

Splenomegaly

Abnormal increased size of the spleen.


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PMID (PMCID)
7871990
 MALE
Kawasaki disease with a concomitant primary Epstein-Barr virus infection.
Kanegane H, Tsuji T, Seki H, Yachie A, Yokoi T, Miyawaki T, Taniguchi N.
Acta Paediatr Jpn. 1994;36(6):713-6.
A two year old boy exhibited not only clinical manifestations which suggested a recurrence of Kawasaki disease (KD) but also evidence of a primary infection by Epstein-Barr virus (EBV) including tonsillitis, splenomegaly and atypical lymphocytosis in the peripheral blood.