Dubin-Johnson syndrome

Dubin-Johnson syndrome (DJS) is a benign, inherited liver disorder characterized clinically by chronic, predominantly conjugated, hyperbilirubinemia and histopathologically by black-brown pigment deposition in parenchymal liver cells.

Portal hypertension

Increased pressure in the portal vein.


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PMID (PMCID)
12118928
 MALE Adult
Association of Dubin-Johnson syndrome and portal vein thrombosis.
Makharia GK, Garg PK, Gupta SD, Tandon RK.
Indian J Gastroenterol. 2002;21(3):118-9.
We report a 22-year-old man who had recurrent episodes of jaundice (conjugated hyperbilirubinemia) because of Dubin-Johnson syndrome and portal hypertension secondary to portal vein thrombosis.
12118928
 MALE Adult
Association of Dubin-Johnson syndrome and portal vein thrombosis.
Makharia GK, Garg PK, Gupta SD, Tandon RK.
Indian J Gastroenterol. 2002;21(3):118-9.
Dubin-Johnson syndrome is neither complicated by liver cell necrosis nor associated with portal hypertension.