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Mandibuloacral dysplasia

Mandibuloacral dysplasia (MAD) is a rare genetic bone disorder characterized by growth delay, postnatal development of craniofacial anomalies including mandibular hypoplasia, progressive acral osteolysis, mottled or patchy pigmentation, skin atrophy, and partial or generalized lipodystrophy.

Diabetes mellitus

A group of abnormalities characterized by hyperglycemia and glucose intolerance.

Total: 2

(per page)

PMID (PMCID)
1736653	MALE	Adult
	Severe insulin resistance and diabetes mellitus in mandibuloacral dysplasia.
	Freidenberg GR, Cutler DL, Jones MC, Hall B, Mier RJ, Culler F, Jones KL, Lozzio C, Kaufmann S. Am J Dis Child. 1992;146(1):93-9.
	Severe insulin resistance and diabetes mellitus in mandibuloacral dysplasia.
1939519	MALE
	Insulin-resistant diabetes mellitus and hypermetabolism in mandibuloacral dysplasia: a newly recognized form of partial lipodystrophy.
	Cutler DL, Kaufmann S, Freidenberg GR. J Clin Endocrinol Metab. 1991;73(5):1056-61.
	Mandibuloacral dysplasia (MAD) is a syndrome characterized by partial lipodystrophy and a distinct phenotype, which includes progressive osteolysis of the mandible and clavicles, cutaneous atrophy, joint contractures, and diabetes mellitus.