Superficial siderosis

Superficial siderosis is a rare neurologic disease characterized by progressive sensorineural hearing loss, cerebellar ataxia, pyramidal signs, and neuroimaging findings revealing hemosiderin deposits in the spinal and cranial leptomeninges and subpial layer. The disease progresses slowly and patients may present with mild cognitive impairment, nystagmus, dysmetria, spasticity, dysdiadochokinesia, dysarthria, hyperreflexia, and Babinski signs. Additional features reported include dementia, urinary incontinence, anosmia, ageusia, and anisocoria.

Anosmia

An inability to perceive odors. This is a general term describing inability to smell arising in any part of the process of smelling from absorption of odorants into the nasal mucous overlying the olfactory epithelium, diffusion to the cilia, binding to olfactory receptor sites, generation of action potentials in olfactory neurons, and perception of a smell.


Total: 2

                      


(per page)
PMID (PMCID)
24250906
(3829287)
OTHER
Superficial siderosis: A rare case of ataxia and otoneurological manifestations.
Assarzadegan F, Ehsanpour E, Hosseini B, Beladi-Moghadam N, Mansouri B, Hesami O.
Iran J Neurol. 2013;12(2):69-71.
We present a 33-year-old man with complete deafness in left ear, partial hearing loss in right ear, gait imbalance, bilateral frontotemporal throbbing headache and anosmia resulted from superficial siderosis.
11727238
FEMALE Middle Aged
[Superficial siderosis of the central nervous system: an uncommon cause of spastic paraparesia].
Carod-Artal FJ, Viana-Brandi I, de Melo CM.
Rev Neurol. 2001;33(6):548-52.
Superficial siderosis of the central nervous system (CNS) is an uncommon neurological condition, characterized clinically by cerebellar ataxia, neurosensorial deafness, anosmia, myelopathy and cognitive deterioration.