Melnick-Needles syndrome

Melnick-Needles syndrome (MNS) belongs to the otopalatodigital syndrome spectrum disorder and is associated with a short stature, facial dysmorphism, osseous abnormalities involving the majority of the axial and appendicular skeleton resulting in impaired speech and masticatory problems.

Decreased response to growth hormone stimuation test

Insufficient production of growth hormone, which is produced by the anterior pituitary gland. Growth hormone is a major participant in control of growth and metabolism.


Total: 3

                       


(per page)
PMID (PMCID)
21274303
(3005751)
 FEMALE Child
Melnick-Needles syndrome associated with growth hormone deficiency: a case report.
Akn L, Adal E, Akn MA, Kurtoglu S.
J Clin Res Pediatr Endocrinol. 2009;1(5):248-51.
There is only one reported case of Melnick-Needles syndrome associated with growth hormone deficiency.
21274303
(3005751)
 FEMALE Child
Melnick-Needles syndrome associated with growth hormone deficiency: a case report.
Akn L, Adal E, Akn MA, Kurtoglu S.
J Clin Res Pediatr Endocrinol. 2009;1(5):248-51.
Melnick-Needles syndrome associated with growth hormone deficiency: a case report.
21274303
(3005751)
 FEMALE Child
Melnick-Needles syndrome associated with growth hormone deficiency: a case report.
Akn L, Adal E, Akn MA, Kurtoglu S.
J Clin Res Pediatr Endocrinol. 2009;1(5):248-51.
Presenting this second case of Melnick-Needles syndrome associated with growth hormone deficiency, we suggest that this association may be coincidental, but that it may also be a consequence of craniofacial abnormalities or an independent component of the disorder.