Meningioma

A rare, mostly benign, primary tumor of the meninges (arachnoid cap cells), usually located in the supratentorial compartment, commonly appearing in the sixth and seventh decade of life, clinically silent in most cases or causing hyperostosis close to the tumor and resulting in focal bulging and localized pain in less than 10% of cases. Additional features may include headache, seizures, gradual personality changes (apathy and dementia), anosmia, impaired vision, exophthalmos, hearing loss, ataxia, dysmetria, hypotonia, nystagmus, and rarely spontaneous bleeding.

Extramedullary hematopoiesis

The process of hematopoiesis occurring outside of the bone marrow (in the liver, thymus, and spleen) in the postnatal organisms.

Total: 6

(per page)

PMID (PMCID)
23610149	FEMALE
	Intracranial extramedullary hematopoiesis associated with multiple myeloma.
	Palma JA, Dominguez PD, Riverol M. Neurology. 2013;80(17):1620.
	Differential diagnosis included tumors (meningiomas, leukemia), subdural hematomas, and intracranial hemorrhages; the lesion's multiplicity and morphology were consistent with intracranial extramedullary hematopoiesis (IEH) (figure).
17714768	MALE
	Extramedullary hematopoeisis within a convexity meningioma.
	Mathews MS, Duma CM, Brant-Zawadzki M, Hasso A, Westhout FD, Klein DJ, Vanhorn D. Surg Neurol. 2008;69(5):522-5; discussion 525.
	Various theories may explain the occurrence of extramedullary hematopoiesis occurring within a meningioma in our patient, such as hematopoietic differentiation of multipotent mesenchymal tumor cells; direct extension of hematopoietic activity from the neighboring marrow cavity; displacement from bone marrow of stem cells that settle and develop in tissues where capillaries and blood vessels proliferate, such as a meningioma; or congenital heterotopia of totipotent connective tissue cells, which, under certain circumstances, may transform into hematopoietic tissue.
17714768	MALE
	Extramedullary hematopoeisis within a convexity meningioma.
	Mathews MS, Duma CM, Brant-Zawadzki M, Hasso A, Westhout FD, Klein DJ, Vanhorn D. Surg Neurol. 2008;69(5):522-5; discussion 525.
	Occurrence of extramedullary hematopoiesis within a meningioma is extremely rare.
17714768	MALE
	Extramedullary hematopoeisis within a convexity meningioma.
	Mathews MS, Duma CM, Brant-Zawadzki M, Hasso A, Westhout FD, Klein DJ, Vanhorn D. Surg Neurol. 2008;69(5):522-5; discussion 525.
	Various theories may explain the occurrence of extramedullary hematopoiesis occurring within a meningioma in our patient, such as hematopoietic differentiation of multipotent mesenchymal tumor cells; direct extension of hematopoietic activity from the neighboring marrow cavity; displacement from bone marrow of stem cells that settle and develop in tissues where capillaries and blood vessels proliferate, such as a meningioma; or congenital heterotopia of totipotent connective tissue cells, which, under certain circumstances, may transform into hematopoietic tissue.
6633840	MALE	Middle Aged
	Extramedullary hematopoiesis in a malignant meningioma.
	Gregorios JB, Bay JW, Dudley AW Jr. Neurosurgery. 1983;13(4):447-51.
	Extramedullary hematopoiesis in a malignant meningioma.
7093826	MALE	Adult
	Extramedullary hematopoiesis simulating parasagittal meningioma.
	Kandel RA, Pritzker KP, Gordon AS, Bilbao JM. Can J Neurol Sci. 1982;9(1):49-51.
	Although clinically and radiologically simulating a meningioma, biopsy revealed extramedullary hematopoiesis involving the falx cerebri.