Meningioma

A rare, mostly benign, primary tumor of the meninges (arachnoid cap cells), usually located in the supratentorial compartment, commonly appearing in the sixth and seventh decade of life, clinically silent in most cases or causing hyperostosis close to the tumor and resulting in focal bulging and localized pain in less than 10% of cases. Additional features may include headache, seizures, gradual personality changes (apathy and dementia), anosmia, impaired vision, exophthalmos, hearing loss, ataxia, dysmetria, hypotonia, nystagmus, and rarely spontaneous bleeding.

Osteolysis

Osteolysis refers to the destruction of bone through bone resorption with removal or loss of calcium.

Total: 5

(per page)

PMID (PMCID)
21354842	MALE
	Feline intracranial meningioma with skull erosion and tumour extension into an area of skull hyperostosis.
	Gutierrez-Quintana R, Gunn-Moore DA, Lamm CG, Penderis J. J Feline Med Surg. 2011;13(4):296-9.
	Evidence of osteolysis with extension of meningioma into, and in some cases through, the region of skull hyperostosis is much less commonly described in human patients.
15068175	MIXED_SAMPLE
	Extracranially extended meningothelial meningiomas with a high MIB-1 index: a report of two cases.
	Yamada SM, Yamada S, Takahashi H, Teramoto A, Matsumoto K. Neuropathology. 2004;24(1):66-71.
	Meningiomas that extend from the meninges to the extracranial tissue and result in skull osteolysis have been known to take an aggressive clinical course.
12955368	MALE	Adult
	The CT triad of malignancy in meningioma--redefinition, with a report of three new cases.
	Grover SB, Aggarwal A, Uppal PS, Tandon R. Neuroradiology. 2003;45(11):799-803.
	The CT triad of extracranial soft-tissue tumour, underlying osteolysis and an intracranial tumour was reported as a sign of malignancy in meningioma, by Younis and Sawaya in 1992.
10068194	FEMALE	Middle Aged
	Ectopic dural osteolytic meningiomas.
	Qasho R, Celli P. Neurosurg Rev. 1998;21(4):295-8.
	The authors describe the case of a small meningioma adhering to the external dural layer without involvement of the internal layer, accompanied by osteolysis of the internal surface of the skull.
1614599	MIXED_SAMPLE
	Intracranial osteolytic malignant meningiomas appearing as extracranial soft-tissue masses.
	Younis G, Sawaya R. Neurosurgery. 1992;30(6):932-5.
	We propose that a meningioma causing osteolysis and soft-tissue extension should be considered malignant until proven otherwise.