Choroid plexus carcinoma

Choroid plexus carcinoma is a rare and highly aggressive malignant type of choroid plexus tumor (see this term) occurring almost exclusively in children, presenting with cerebrospinal fluid obstruction in the lateral ventricles (most common), the fourth and third ventricles or in multiple ventricles, leading to hydrocephalus and increased intracranial pressure, and manifesting with nausea, vomiting, abnormal eye movements, gait impairment, seizures and enlarged head circumference.

Melanoma

The presence of a melanoma, a malignant cancer originating from pigment producing melanocytes. Melanoma can originate from the skin or the pigmented layers of the eye (the uvea).


Total: 3

                       


(per page)
PMID (PMCID)
24251760
 MALE Infant
Spitzoid melanoma in a child with Li-Fraumeni syndrome.
Kollipara R, Cooley LD, Horii KA, Hetherington ML, Leboit PE, Singh V, Zwick DL.
Pediatr Dev Pathol. 2014;17(1):64-9.
We report the occurrence of choroid plexus carcinoma, Spitzoid melanoma, and myelodysplasia in a child who was found to carry a germline mutation for TP53.
24251760
 MALE Infant
Spitzoid melanoma in a child with Li-Fraumeni syndrome.
Kollipara R, Cooley LD, Horii KA, Hetherington ML, Leboit PE, Singh V, Zwick DL.
Pediatr Dev Pathol. 2014;17(1):64-9.
While choroid plexus carcinoma and myelodysplasia have relatively frequently been described, melanomas have been very rarely described in Li-Fraumeni syndrome.
17695766
 MALE Child
[Li-Fraumeni familial cancer syndrome: case report and review of the literature].
Tena Sanabria ME, Herrera Sanchez D, Hernandez Lopez J, Huicochea Montiel JC, Rodriguez A.
Acta Ortop Mex. 2007;21(2):99-104.
Eight-and-a-half year-old child with a history of a CNS tumor (choroid plexus carcinoma) and two years later, a melanoma (Spitz nevus).