POEMS syndrome

POEMS syndrome is a paraneoplastic syndrome characterized by polyradiculoneuropathy (P), organomegaly (O), endocrinopathy (E), clonal plasma cell disorder (M), and skin changes (S). Other features include papilledema, extravascular volume overload, sclerotic bone lesions, thrombocytosis/erythrocytosis, and elevated VEGF levels.

Stroke

Sudden impairment of blood flow to a part of the brain due to occlusion or rupture of an artery to the brain.


Total: 9

                       


(per page)
PMID (PMCID)
30273192
 FEMALE Middle Aged
Increased Risk of Ischemic Stroke in Multiple Myeloma Associated With Lenalidomide Treatment: A Case Report and Review of the Literature.
de Celis E, Alonso de Lecinana M, Rodriguez-Pardo J, Fuentes B, Diez-Tejedor E.
Clin Neuropharmacol. 2018;41(6):232-235.
A literature review provided 84 reports from the license holder, 2 more cases of stroke in patients with MM receiving lenalidomide and a recurrent stroke in a patient experiencing polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS syndrome) treated with lenalidomide.
30273192
 FEMALE Middle Aged
Increased Risk of Ischemic Stroke in Multiple Myeloma Associated With Lenalidomide Treatment: A Case Report and Review of the Literature.
de Celis E, Alonso de Lecinana M, Rodriguez-Pardo J, Fuentes B, Diez-Tejedor E.
Clin Neuropharmacol. 2018;41(6):232-235.
A literature review provided 84 reports from the license holder, 2 more cases of stroke in patients with MM receiving lenalidomide and a recurrent stroke in a patient experiencing polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS syndrome) treated with lenalidomide.
30310290
(6166759)
 OTHER
POEMS syndrome complicated with multiple ischemic vascular events: case report and review of literature.
Gaman M, Vladareanu AM, Dobrea C, Onisai M, Marinescu C, Cisleanu D, Ciufu C, Vasile D, Bumbea H, Voican I.
Onco Targets Ther. 2018;11:6271-6276.
We hereby report a patient with POEMS syndrome accompanied by CD who presented recurrent strokes and splenic infarction.
28664017
(5364899)
 OTHER
Coexistence of Quasi-moyamoya Disease and POEMS Syndrome in a Patient with Intracranial Hemorrhage: A Case Report and Literature Review.
Yamaguchi I, Satomi J, Yamamoto N, Yoshioka S, Tada Y, Yagi K, Kanematsu Y, Nagahiro S.
NMC Case Rep J. 2017;4(1):5-9.
We suggest that the POEMS syndrome be ruled out in the differential diagnosis of patients presenting with atypical stroke, multivessel stenotic lesions (moyamoya vessels), and polyneuropathy.
22427283
 MIXED_SAMPLE Adult
Therapeutic challenges in a patient with POEMS syndrome and recurrent stroke: presentation of a case and review of the literature.
Sommer B, Schaumberg J.
Acta Neurol Belg. 2012;112(1):9-13.
Therapeutic challenges in a patient with POEMS syndrome and recurrent stroke: presentation of a case and review of the literature.
18035247
 MIXED_SAMPLE Middle Aged
Recurrent strokes in two patients with POEMS syndrome and Castleman's disease.
Garcia T, Dafer R, Hocker S, Schneck M, Barton K, Biller J.
J Stroke Cerebrovasc Dis. 2007;16(6):278-84.
However, only 3 patients have ever been described with POEMS syndrome, Castleman's disease, and stroke.
15007508
 FEMALE Adult
[Recurrent cerebral ischemias due to cerebral vasculitis within the framework of incomplete POEMS syndrome with Castleman disease].
Rossler M, Kiessling B, Klotz JM, Langohr HD.
Nervenarzt. 2004;75(8):790-4.
There are only few reports dealing with cerebral strokes and POEMS syndrome.
12756139
 MIXED_SAMPLE Adult
POEMS syndrome associated with ischemic stroke.
Kang K, Chu K, Kim DE, Jeong SW, Lee JW, Roh JK.
Arch Neurol. 2003;60(5):745-9.
The POEMS syndrome can be associated with stroke, particularly end artery border-zone infarctions.
9700780
 MALE Middle Aged
[Recurrent cerebrovascular insult--manifestation of POEMS syndrome?].
Forster A, Muri R.
Schweiz Med Wochenschr. 1998;128(26):1059-64.
Recurrent strokes may therefore represent a further complication of the POEMS syndrome.