POEMS syndrome

POEMS syndrome is a paraneoplastic syndrome characterized by polyradiculoneuropathy (P), organomegaly (O), endocrinopathy (E), clonal plasma cell disorder (M), and skin changes (S). Other features include papilledema, extravascular volume overload, sclerotic bone lesions, thrombocytosis/erythrocytosis, and elevated VEGF levels.

Pancytopenia

An abnormal reduction in numbers of all blood cell types (red blood cells, white blood cells, and platelets).


Total: 1

                       


(per page)
PMID (PMCID)
28906499
 MALE Adult
[Incomplete POEMS syndrome with multicentric Castleman's disease].
Gonzalez de la Aleja P, Garcia-Navarro M, Sanchez-Martinez R, Ramos JM.
An Sist Sanit Navar. 2017;40(3):475-478.
CD may present severe pancytopenia, multi-organ failure, lymphoma evolution and it can sometimes be associated with paraneoplastic syndromes such as POEMS syndrome.