POEMS syndrome

POEMS syndrome is a paraneoplastic syndrome characterized by polyradiculoneuropathy (P), organomegaly (O), endocrinopathy (E), clonal plasma cell disorder (M), and skin changes (S). Other features include papilledema, extravascular volume overload, sclerotic bone lesions, thrombocytosis/erythrocytosis, and elevated VEGF levels.

Vascular calcification

Abnormal calcification of the vasculature.


Total: 2

                       


(per page)
PMID (PMCID)
20847836
(2940264)
 OTHER
Calciphylaxis as a Catastrophic Complication in a Patient with POEMS Syndrome.
Hineno A, Kinoshita T, Kinoshita M, Arakura F, Naito KS, Shimojima Y, Matsuda M, Yoshida K, Ikeda SI.
Case Rep Neurol. 2009;1(1):47-53.
The pathogenic link between POEMS syndrome and calciphylaxis is still unclear, but VEGF is known to regulate vascular calcification, in cooperation with bone morphogenetic proteins.
3920544
 MALE Adult
Osteosclerotic myeloma complicated by diffuse arteritis, vascular calcification and extensive cutaneous necrosis.
Raper RF, Ibels LS.
Nephron. 1985;39(4):389-92.
Osteosclerotic myeloma complicated by diffuse arteritis, vascular calcification and extensive cutaneous necrosis.