POEMS syndrome

POEMS syndrome is a paraneoplastic syndrome characterized by polyradiculoneuropathy (P), organomegaly (O), endocrinopathy (E), clonal plasma cell disorder (M), and skin changes (S). Other features include papilledema, extravascular volume overload, sclerotic bone lesions, thrombocytosis/erythrocytosis, and elevated VEGF levels.

Peripheral edema

An abnormal accumulation of interstitial fluid in the soft tissues of the limbs.


Total: 3

                       


(per page)
PMID (PMCID)
31119772
 OTHER
Adenopathy and extensive skin patch overlying a plasmacytoma with unusual histologic findings in a patient with polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes syndrome and Castleman disease.
Dagrosa AT, Cowdrey MCE, LeBlanc RE, Lansigan F, Kaur P, Carter JB.
J Cutan Pathol. 2019;:.
The patient subsequently developed polyneuropathy and peripheral edema, which supported an additional diagnosis of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes (POEMS) syndrome.
8286834
 FEMALE Middle Aged
Crow-Fukase syndrome associated with pulmonary hypertension.
Iwasaki H, Ogawa K, Yoshida H, Takashima F, Shimizu K, Lee JD, Ueda T, Nakamura T.
Intern Med. 1993;32(7):556-60.
These findings suggest the possibility that patients with Crow-Fukase syndrome have cardiopulmonary disorders including PH and cardiomegaly which might cause some cardiovascular symptoms such as peripheral edema and finger clubbing.
1942531
 FEMALE
[Progression from Crow-Fukase syndrome with double gammopathy (IgM-kappa, IgG-lambda) to primary macroglobulinemia].
Fujii H, Yashige H, Kanoh T, Urata Y.
Rinsho Ketsueki. 1991;32(8):890-6.
The patient was diagnosed as having Crow-Fukase syndrome from the following data: albumin-cytologic dissociation of cerebrospinal fluid, peripheral edema, diffuse hyperpigmentation of the skin, diabetic glucose intolerance, serum double gammopathy (IgM-kappa, IgG-lambda) and hepatomegaly.