Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Osteopenia

Osteopenia is a term to define bone density that is not normal but also not as low as osteoporosis. By definition from the World Health Organization osteopenia is defined by bone densitometry as a T score -1 to -2.5.


Total: 3

                       


(per page)
PMID (PMCID)
19260386
 MALE Adult
Occult large epiphyseal solitary plasmacytoma at multidetector row computer tomography detected by magnetic resonance imaging.
De Filippo M, Pogliacomi F, Albisinni U, Quinto S, Bocchi C, Sverzellati N, Lipia S, Zompatori M.
Acta Biomed. 2008;79(3):240-5.
Myeloma may be distinguished at radiological imaging in four distinct types: single osseous lesions (solitary plasmacytoma), diffused skeletal effects (myelomatosis), diffused osteopenia and sclerosing myeloma.
16431064
 MIXED_SAMPLE Middle Aged
Atypical manifestations of multiple myeloma: radiological appearance.
Hess T, Egerer G, Kasper B, Rasul KI, Goldschmidt H, Kauffmann GW.
Eur J Radiol. 2006;58(2):280-5.
Diagnostic procedures performed on patients with multiple myeloma typically reveal lytic bone lesions, osteopenia or osteoporosis, bone marrow infiltration by plasma cells as well as overproduction of immunoglobulin or light chains in the serum or urine.
10665349
 MALE Middle Aged
Association of posterior rib fractures with exaggerated kyphosis and sternal collapse.
Muldoon K, Chu P, Pathria M, Resnick D.
Clin Imaging. 1999;23(5):311-3.
We present a case of a 62-year-old man with multiple myeloma and osteopenia who sustained fractures to all three components.