Name: PubCaseFinder
License: http://creativecommons.org/licenses/by/2.1/jp/
Keywords: PubCaseFinder,PCF,Rare Disease,Phenotype,Gene,Match,Assist

Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Cholestasis

Impairment of bile flow due to obstruction in bile ducts.

Total: 5

(per page)

PMID (PMCID)
15184335	MALE	Middle Aged
	Multiple myeloma in a patient with fever of unknown origin and cholestasis.
	Mumoli N, Cei M, Incensati R, Verzuri S. CMAJ. 2004;170(12):1809-10.
	We report a case of multiple myeloma in a patient presenting with a long-standing fever and cholestasis.
15184335	MALE	Middle Aged
	Multiple myeloma in a patient with fever of unknown origin and cholestasis.
	Mumoli N, Cei M, Incensati R, Verzuri S. CMAJ. 2004;170(12):1809-10.
	Multiple myeloma is not usually included in the differential diagnosis, nor is it considered a frequent cause of cholestasis in the absence of amyloidosis.
15184335	MALE	Middle Aged
	Multiple myeloma in a patient with fever of unknown origin and cholestasis.
	Mumoli N, Cei M, Incensati R, Verzuri S. CMAJ. 2004;170(12):1809-10.
	Multiple myeloma in a patient with fever of unknown origin and cholestasis.
11991600	MALE	Adult
	Light chain deposition disease of the liver without renal involvement in a patient with multiple myeloma related to liver failure and rapid fatal outcome.
	Michopoulos S, Petraki K, Petraki C, Dimopoulos MA. Dig Dis Sci. 2002;47(4):730-4.
	We describe a 36-year-old man with advanced multiple myeloma (Salmon and Durie stage III) who developed jaundice and severe cholestasis after a first cure with systemic chemotherapy of vincristine, doxorubicin, and oral dexamethasone (VAD).
8525344	MIXED_SAMPLE	Adult
	[Pruritus--also a challenge in internal medicine].
	Brunner W. Schweiz Med Wochenschr. 1995;125(46):2244-50.
	Other important causes must be considered; all forms of cholestasis, including primary biliary cirrhosis, drug-induced, pregnancy-related, and extrahepatic cholestasis; other hematologic and malignant disorders such as non-Hodgkin's lymphoma, leukemia, multiple myeloma, solid tumors, and myelodysplastic syndromes; metabolic and endocrine diseases, most notably diabetes mellitus, hyperthyroidism, hypothyroidism, and carcinoid syndrome; focal neurologic diseases such as brain tumors, cerebral infarctions and multiple sclerosis; adverse drug reactions without rash; infectious diseases, especially parasitic and HIV infections.