Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Ascites

Accumulation of fluid in the peritoneal cavity.


Total: 27

                      


(per page)
PMID (PMCID)
28875827
FEMALE Adult
Multiple Myeloma Associated Intestinal Amyloidosis: Intestinal Pseudoobstruction Falsely Considered as an Ascites.
Milivojevic V, Stojanovic M, Rankovic I, Micev M, Vukicevic RJ, Milosavljevic T.
Rev Recent Clin Trials. 2018;13(1):79-81.
Multiple Myeloma Associated Intestinal Amyloidosis: Intestinal Pseudoobstruction Falsely Considered as an Ascites.
29991097
OTHER
Multiple Myeloma Light Chain Amyloidosis Presenting as Hepatic Failure.
Elgouhari H, Ahmed K, Niazi M, Huntington MK.
S D Med. 2018;71(3):112-115.
We report here a case of portal hypertension, ascites, and severe intrahepatic cholestasis as the initial presentation of hepatic amyloidosis and multiple myeloma, which followed a rapidly progressive clinical course.
29151500
(5874348)
MALE Middle Aged
Nonmyelomatous Ascites Resulting from the Increased Secretion of Vascular Endothelial Growth Factor in Multiple Myeloma.
Maki H, Nannya Y, Imai Y, Yamaguchi S, Kamikubo Y, Ichikawa M, Nakamura F, Kurokawa M.
Intern Med. 2018;57(5):725-727.
Nonmyelomatous Ascites Resulting from the Increased Secretion of Vascular Endothelial Growth Factor in Multiple Myeloma.
29151500
(5874348)
MALE Middle Aged
Nonmyelomatous Ascites Resulting from the Increased Secretion of Vascular Endothelial Growth Factor in Multiple Myeloma.
Maki H, Nannya Y, Imai Y, Yamaguchi S, Kamikubo Y, Ichikawa M, Nakamura F, Kurokawa M.
Intern Med. 2018;57(5):725-727.
Ascites is a rare complication of multiple myeloma (MM); in most cases, the direct invasion of myeloma cells to the peritoneal cavity has been assumed to be the etiology because the effusion is usually exudative and contains a high proportion of myeloma cells.
28512393
(5422736)
OTHER
Immunoglobulin A Lambda Multiple Myeloma in a Patient with HIV: An Unusual Cause of Massive Ascites.
Abdulsamad M, Abbas N, Patel H, Balar B, Khaja M.
Case Rep Gastroenterol. 2017;11(1):201-206.
Immunoglobulin A Lambda Multiple Myeloma in a Patient with HIV: An Unusual Cause of Massive Ascites.
26306073
OTHER
IgG Lambda Myeloma Presenting as Plasmacytic Ascites: Case Report and Review of Literature.
Mitra S, Mukherjee S, Chakraborty H, Bhattacharyya M.
Indian J Hematol Blood Transfus. 2015;31(4):472-9.
Ascites may develop very rarely during the course of disease in multiple myeloma.
26306073
OTHER
IgG Lambda Myeloma Presenting as Plasmacytic Ascites: Case Report and Review of Literature.
Mitra S, Mukherjee S, Chakraborty H, Bhattacharyya M.
Indian J Hematol Blood Transfus. 2015;31(4):472-9.
We report the case of a 78years old male with IgG lambda multiple myeloma who initially presented with plasmacytic ascites.
20150504
FEMALE
Recurrent capillary leak syndrome following bortezomib therapy in a patient with relapsed myeloma.
Hsiao SC, Wang MC, Chang H, Pei SN.
Ann Pharmacother. 2010;44(3):587-9.
A 65-year-old female with relapsed multiple myeloma developed fluid retention, ascites, and general anasarca following bortezomib administration (1.3 mg/m(2) on days 1, 4, 8, and 11).
18981637
MALE Middle Aged
Multiple myeloma presenting initially with pleural effusion and a unique paraspinal tumor in the thorax.
Yokoyama T, Tanaka A, Kato S, Aizawa H.
Intern Med. 2008;47(21):1917-20.
We herein report an extremely rare case of a patient with IgD-lambda positive multiple myeloma presenting with myelomatous pleural effusion and ascites.
18432366
FEMALE Middle Aged
[Myelomatous ascites].
Young P, Finn BB, Pellegrini D, Bruetman JE, Shanley CM, Tolosa Vilell C, Trimarchi H.
An Med Interna. 2008;25(2):85-9.
Ascites is rare in patients with multiple myeloma (MM).
15863214
FEMALE Middle Aged
Multiple myeloma presenting initially as a solitary pleural effusion later complicated by malignant plasmacytic ascites.
Inoue Y, Chua K, McClure RF, Jimenez MC, Gocke CD, Badros AZ, Takebe N.
Leuk Res. 2005;29(6):715-8.
To the best of our knowledge after an extensive medical literature review, this case is the first one of multiple myeloma presenting with a plasmacytic pleural effusion, a negative bone marrow, and a late complication of plasmacytic ascites.
15863214
FEMALE Middle Aged
Multiple myeloma presenting initially as a solitary pleural effusion later complicated by malignant plasmacytic ascites.
Inoue Y, Chua K, McClure RF, Jimenez MC, Gocke CD, Badros AZ, Takebe N.
Leuk Res. 2005;29(6):715-8.
A pleural effusion is a rare presenting feature of multiple myeloma and can be a complication of myelomatous ascites as well.
15863214
FEMALE Middle Aged
Multiple myeloma presenting initially as a solitary pleural effusion later complicated by malignant plasmacytic ascites.
Inoue Y, Chua K, McClure RF, Jimenez MC, Gocke CD, Badros AZ, Takebe N.
Leuk Res. 2005;29(6):715-8.
Multiple myeloma presenting initially as a solitary pleural effusion later complicated by malignant plasmacytic ascites.
10455378
FEMALE Middle Aged
Massive myelomatous ascites responsive to VAD chemotherapy and autologous stem cell transplantation.
Alegre A, Martinez-Chamorro C, Fernandez-Ranada JM.
Bone Marrow Transplant. 1999;24(3):343-4.
Plasmacytic ascites is an infrequent complication of multiple myeloma.
10455378
FEMALE Middle Aged
Massive myelomatous ascites responsive to VAD chemotherapy and autologous stem cell transplantation.
Alegre A, Martinez-Chamorro C, Fernandez-Ranada JM.
Bone Marrow Transplant. 1999;24(3):343-4.
We describe a patient with plasmacytic ascites and quiescent multiple myeloma of 8 years of duration.
9929107
FEMALE
Myeloma ascites--a favorable outcome with cyclophosphamide therapy.
Keren D, Schliamser L, Atias D, Yeshurun D, Zuckerman E.
Am J Hematol. 1999;60(2):140-2.
A 71-year-old woman with multiple myeloma (MM) in remission was admitted for evaluation of recent abdominal distension and was diagnosed as having massive myeloma ascites.
8847807
MALE
[Massive ascites as an initial sign, plasmacytoma of the cervical supine, and hyperammonemic consciousness disturbance in a patient with biclonal type multiple myeloma].
Ohmoto A, Kohno M, Yasukawa K, Matsuyama R.
Rinsho Ketsueki. 1996;37(4):346-51.
So he was diagnosed as multiple myeloma presenting biclonal gammopathy of IgA-L and IgD-K. Ascites was massive and drainage of 2 to 4 liter per week was required.
8847807
MALE
[Massive ascites as an initial sign, plasmacytoma of the cervical supine, and hyperammonemic consciousness disturbance in a patient with biclonal type multiple myeloma].
Ohmoto A, Kohno M, Yasukawa K, Matsuyama R.
Rinsho Ketsueki. 1996;37(4):346-51.
Ascites was supposed to be related to multiple myeloma, because the IL-6 level in the ascites was increased (2,440 pg/ml), although repeated cytologic studies were negative.
8847807
MALE
[Massive ascites as an initial sign, plasmacytoma of the cervical supine, and hyperammonemic consciousness disturbance in a patient with biclonal type multiple myeloma].
Ohmoto A, Kohno M, Yasukawa K, Matsuyama R.
Rinsho Ketsueki. 1996;37(4):346-51.
Ascites was supposed to be related to multiple myeloma, because the IL-6 level in the ascites was increased (2,440 pg/ml), although repeated cytologic studies were negative.
8847807
MALE
[Massive ascites as an initial sign, plasmacytoma of the cervical supine, and hyperammonemic consciousness disturbance in a patient with biclonal type multiple myeloma].
Ohmoto A, Kohno M, Yasukawa K, Matsuyama R.
Rinsho Ketsueki. 1996;37(4):346-51.
[Massive ascites as an initial sign, plasmacytoma of the cervical supine, and hyperammonemic consciousness disturbance in a patient with biclonal type multiple myeloma].