Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Splenomegaly

Abnormal increased size of the spleen.


Total: 4

                       


(per page)
PMID (PMCID)
30906609
 OTHER
A 30-Year-Old Carrier of Gaucher Disease with Multiple Myeloma.
Chadha J, Sahai T, Schwimmer J, Shani D.
Case Rep Oncol Med. 2019;2019:6469196.
We are reporting a case of a 30-year-old male with no past medical history who presented with new onset of renal failure, anemia, and splenomegaly and was diagnosed with multiple myeloma.
19337840
 FEMALE Middle Aged
Hematologic neoplasias and acromegaly.
Barbosa FR, Vieira Neto L, Lima GA, Wildemberg LE, Portugal R, Gadelha MR.
Pituitary. 2011;14(4):377-81.
We report a 59-year-old acromegalic woman, who presented with generalized bone pain, weakness, fatigue and foamy urine, who was found to have multiple myeloma (MM); and a 60-year-old acromegalic woman with dizziness, vomiting and abdominal pain, high blood pressure and splenomegaly that was posteriorly diagnosed as having Waldenstrom's macroglobulinemia (WM).
15048003
 MIXED_SAMPLE Middle Aged
Unusual haematological alterations in rheumatoid arthritis.
Agarwal V, Sachdev A, Lehl S, Basu S.
J Postgrad Med. 2004;50(1):60-1.
These patients were detected to have pure red cell aplasia (PRCA) (normocytic normochromic anaemia, reticulocytopenia and absence of erythroid precursors in the bone marrow), immune thrombocytopenia (IT) (absence of splenomegaly and presence of increased megakaryocytes in the bone marrow) and multiple myeloma (MM) (lytic lesions on skull, paraproteinaemia and bone marrow plasmacytosis) respectively.
6433500
 MIXED_SAMPLE Adult
[Rare forms of paraproteinemic hemoblastosis].
Andreeva NE.
Ter Arkh. 1984;56(6):59-63.
The paper is concerned with 10 cases of multiple myeloma with myeloid (myeloma-myeloid) splenomegaly and myelemia; 4 cases of chronic subleukemic (or aleukemic) lymphocyte plasma cell leukemia with paraproteinemia G which do not differ in the clinical or morphological picture from Waldenstrom's macroglobulinemia ("Waldenstrom's macroglobulinemia without macroglobulinemia"), and 2 cases of macroglobulinemia lymphocyte plasma cell lymphoma of the stomach and lymph nodes of the abdominal cavity with chronic plasma cell leukemia.