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License: http://creativecommons.org/licenses/by/2.1/jp/
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Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Eosinophilia

Increased count of eosinophils in the blood.

Total: 15

(per page)

PMID (PMCID)
30376895 (6208011)	FEMALE
	Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report.
	Oka S, Ono K, Nohgawa M. J Med Case Rep. 2018;12(1):320.
	It is the first case of leukocytoclastic vasculitis and eosinophilia in multiple myeloma that was associated with a T helper type 1/T helper type 2 imbalance and T regulatory cells, and was successfully treated with bortezomib, lenalidomide, and dexamethasone.
30376895 (6208011)	FEMALE
	Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report.
	Oka S, Ono K, Nohgawa M. J Med Case Rep. 2018;12(1):320.
	Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report.
30376895 (6208011)	FEMALE
	Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report.
	Oka S, Ono K, Nohgawa M. J Med Case Rep. 2018;12(1):320.
	An 85-year-old Japanese woman exhibited the rare presentation of multiple myeloma (immunoglobulin kappa chain type) with leukocytoclastic vasculitis and eosinophilia.
28451433 (5404234)	OTHER
	Lenalidomide-induced eosinophilic pneumonia.
	Toma A, Rapoport AP, Burke A, Sachdeva A. Respirol Case Rep. 2017;5(4):e00233.
	We present, to our knowledge, an unusual and first reported case of a patient with relapsed multiple myeloma who received lenalidomide after autologous stem cell transplant, then developed eosinophilic pneumonia presenting as dyspnoea, peripheral eosinophilia, and bilateral pulmonary opacities.
23999760	FEMALE
	A case of DRESS (drug reaction with eosinophilia and systemic symptoms) with acute interstitial nephritis secondary to lenalidomide.
	Shaaban H, Layne T, Guron G. J Oncol Pharm Pract. 2014;20(4):302-4.
	We report a case of a severe 'drug reaction with eosinophilia and systemic symptoms' syndrome associated with acute interstitial nephritis in a patient with multiple myeloma likely related to the administration of lenalidomide.
25332594	OTHER
	Patient with refractory multiple myeloma developing eosinophilia after lenalidomide treatment and lung cancer 9months later: case report and review of the literature.
	Sekiguchi Y, Shimada A, Imai H, Wakabayashi M, Sugimoto K, Nakamura N, Sawada T, Komatsu N, Noguchi M. Indian J Hematol Blood Transfus. 2014;30(Suppl 1):264-70.
	Patient with refractory multiple myeloma developing eosinophilia after lenalidomide treatment and lung cancer 9months later: case report and review of the literature.
25332594	OTHER
	Patient with refractory multiple myeloma developing eosinophilia after lenalidomide treatment and lung cancer 9months later: case report and review of the literature.
	Sekiguchi Y, Shimada A, Imai H, Wakabayashi M, Sugimoto K, Nakamura N, Sawada T, Komatsu N, Noguchi M. Indian J Hematol Blood Transfus. 2014;30(Suppl 1):264-70.
	There have been only five reported cases of eosinophilia caused by lenalidomide used for the treatment of multiple myeloma.
22022299 (3192883)	OTHER
	Successful Chemotherapy Following Autologous Stem Cell Transplantation in Multiple Myeloma and Multi-organ Dysfunction with Infiltration of Eosinophils: A Case Report.
	Lee HS, Park LC, Shin SH, Lee SU, Chang HK, Huh B, Jung GS, Kim MH, Kim YS. Cancer Res Treat. 2011;43(3):199-203.
	Both hematopoietic and solid neoplasms may be associated with peripheral blood eosinophilia, but multiple myeloma is rarely associated with eosinophilia.
22022299 (3192883)	OTHER
	Successful Chemotherapy Following Autologous Stem Cell Transplantation in Multiple Myeloma and Multi-organ Dysfunction with Infiltration of Eosinophils: A Case Report.
	Lee HS, Park LC, Shin SH, Lee SU, Chang HK, Huh B, Jung GS, Kim MH, Kim YS. Cancer Res Treat. 2011;43(3):199-203.
	Both hematopoietic and solid neoplasms may be associated with peripheral blood eosinophilia, but multiple myeloma is rarely associated with eosinophilia.
22022299 (3192883)	OTHER
	Successful Chemotherapy Following Autologous Stem Cell Transplantation in Multiple Myeloma and Multi-organ Dysfunction with Infiltration of Eosinophils: A Case Report.
	Lee HS, Park LC, Shin SH, Lee SU, Chang HK, Huh B, Jung GS, Kim MH, Kim YS. Cancer Res Treat. 2011;43(3):199-203.
	We now report the case of a 31-year-old man with multiple myeloma associated with marked eosinophilia who developed multiple organ dysfunction with infiltration of eosinophils.
7741103	MALE	Middle Aged
	Plasma cell myeloma associated with eosinophilia.
	Glantz L, Rintels P, Samoszuk M, Medeiros LJ. Am J Clin Pathol. 1995;103(5):583-7.
	The association of plasma cell myeloma and eosinophilia is rare.
7741103	MALE	Middle Aged
	Plasma cell myeloma associated with eosinophilia.
	Glantz L, Rintels P, Samoszuk M, Medeiros LJ. Am J Clin Pathol. 1995;103(5):583-7.
	This review of the literature has revealed five cases of plasma cell myeloma associated with eosinophilia described previously.
7741103	MALE	Middle Aged
	Plasma cell myeloma associated with eosinophilia.
	Glantz L, Rintels P, Samoszuk M, Medeiros LJ. Am J Clin Pathol. 1995;103(5):583-7.
	The authors describe a 49-year-old man with plasma cell myeloma and marked absolute peripheral blood eosinophilia, 109.7 x 10(9)/L.
7741103	MALE	Middle Aged
	Plasma cell myeloma associated with eosinophilia.
	Glantz L, Rintels P, Samoszuk M, Medeiros LJ. Am J Clin Pathol. 1995;103(5):583-7.
	In this case, IL-3 secreted either by the neoplastic cells at a level below detection by immunohistochemistry or by other cells in response to the presence of plasma cell myeloma may have played a role in causing the eosinophilia.
7823398	FEMALE
	[Multiple myeloma preceding myelodysplastic syndrome with eosinophilia and der (1;7)].
	Matano S, Kobayashi K, Nakamura S, Yoshida T. Rinsho Ketsueki. 1994;35(11):1310-4.
	[Multiple myeloma preceding myelodysplastic syndrome with eosinophilia and der (1;7)].