Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Spinal cord compression

External mechanical compression of the spinal cord.


Total: 23

                      


(per page)
PMID (PMCID)
26997111
MALE Adult
Multiple myeloma presenting with acute bony spinal cord compression and mechanical instability successfully managed nonoperatively.
Gokaraju K, Butler JS, Benton A, Suarez-Huerta ML, Selvadurai S, Molloy S.
Spine J. 2016;16(8):e567-70.
Multiple myeloma presenting with acute bony spinal cord compression and mechanical instability successfully managed nonoperatively.
26115049
FEMALE
Differentiated plasma cell myeloma presenting as a solitary spinal amyloidoma: a case report, possible pitfall and review to the literature.
Brawanski N, Platz J, Seifert V, Marquardt G, Weise LM.
Clin Neurol Neurosurg. 2015;137:1-4.
Plasma cell myeloma may rarely present as a solitary amyloidoma in the initial pathological examination with the potential to cause spinal cord compression associated to osteolytic lesions of the spine.
24384823
FEMALE
Fear of impending fractures: when to refer? A case-based review.
Kronisch C, Balague F, Dudler J.
Clin Rheumatol. 2015;34(7):1303-9.
The issue of impending fracture of the femurs and risk of spinal cord compression was raised in an 83-year-old woman with multiple myeloma.
25810804
(4364686)
FEMALE Middle Aged
An association of vertebral breast cancer metastasis and multiple myeloma, revealed by a spinal cord compression.
Kherfani A, Amri K, Hachem M, Abid L, Bouaziz M, Mestiri M.
Pan Afr Med J. 2014;19:168.
Authors describe the case of a patient with breast cancer and multiple myeloma as the second metachronous disease responsible for spinal cord compression.
24175035
(3809446)
OTHER
Multiple Myeloma and Epidural Spinal Cord Compression : Case Presentation and a Spine Surgeon's Perspective.
Ha KY, Kim YH, Kim HW.
J Korean Neurosurg Soc. 2013;54(2):151-4.
Image and serological studies revealed multiple myeloma and spinal cord compression caused by epidural myeloma.
24570782
(3932126)
FEMALE Adult
Multiple myeloma revealed by spinal cord compression and herpes zoster in a 36-year-old Cameroonian.
Sini V, Kamtchum TJ, Tegueu CK, Djientcheu Vde P.
Pan Afr Med J. 2013;16:21.
Multiple myeloma revealed by spinal cord compression and herpes zoster in a 36-year-old Cameroonian.
24570782
(3932126)
FEMALE Adult
Multiple myeloma revealed by spinal cord compression and herpes zoster in a 36-year-old Cameroonian.
Sini V, Kamtchum TJ, Tegueu CK, Djientcheu Vde P.
Pan Afr Med J. 2013;16:21.
The authors describe a case of multiple myeloma in a 36-year-old patient revealed by spinal cord compression and Herpes zoster with a rapidly unfavourable outcome.
24176664
FEMALE Middle Aged
Myeloma after local external beam radiotherapy jet: Is it a new entity?
Maalej M, Belaid A, Laabidi M, Ben Romdhane N, Kochbati L.
Cancer Radiother. 2013;17(7):668-70.
Radiation therapy may be indicated in multiple myeloma to relieve pain, alleviate spinal cord compression or reduce tumor mass.
24176664
FEMALE Middle Aged
Myeloma after local external beam radiotherapy jet: Is it a new entity?
Maalej M, Belaid A, Laabidi M, Ben Romdhane N, Kochbati L.
Cancer Radiother. 2013;17(7):668-70.
We report the case of a patient presenting a multiple myeloma, treated with radiation therapy for a spinal cord compression, who developed, eleven months later, an in-field subcutaneous relapse.
23760456
(3678638)
OTHER
Open kyphoplasty in the treatment of a painful vertebral lytic lesion with spinal cord compression caused by multiple myeloma: A case report.
Pan J, Qian ZL, Sun ZY, Yang HL.
Oncol Lett. 2013;5(5):1621-1624.
Open kyphoplasty in the treatment of a painful vertebral lytic lesion with spinal cord compression caused by multiple myeloma: A case report.
21882094
FEMALE Middle Aged
Central nervous system myelomatosis with optic neuropathy and intramedullary spinal cord compression responding to radiation therapy.
Riley JM, Russo JK, Shipp A, Alsharif M, Jenrette JM.
Jpn J Radiol. 2011;29(7):513-6.
Central nervous system myelomatosis with optic neuropathy and intramedullary spinal cord compression responding to radiation therapy.
20691039
(2923176)
OTHER
Multiple myeloma presenting as spinal cord compression: a case report.
Chakraborti C, Miller KL.
J Med Case Rep. 2010;4:251.
Multiple myeloma presenting as spinal cord compression: a case report.
20691039
(2923176)
OTHER
Multiple myeloma presenting as spinal cord compression: a case report.
Chakraborti C, Miller KL.
J Med Case Rep. 2010;4:251.
Surprisingly, the etiology of this case of spinal cord compression was found to be multiple myeloma presenting as a solid tumor.
18831763
(2566563)
OTHER
IgM multiple myeloma presenting with spinal cord compression caused by a plasmacytoma: A case report.
Tahan I, Seale J, Edwards D.
Cases J. 2008;1(1):207.
IgM multiple myeloma presenting with spinal cord compression caused by a plasmacytoma: A case report.
17766137
MALE Adult
Modified transmanubrial osteomuscular sparing approach for resection of T1 vertebral tumor.
Di Rienzo G, Surrente C, Lopez C, Urgese AL.
Eur J Cardiothorac Surg. 2007;32(5):810-2.
The procedure was necessary for treating a patient who presented with an invasion of T1 vertebral body by multiple myeloma with initial neurological symptoms of epidural spinal cord compression.
15576117
MALE
Multiple myeloma-associated solitary epidural amyloidoma of C2-C3 without bony connection or myelopathy: case report and review of the literature.
Belber CJ, Graham DL.
Surg Neurol. 2004;62(6):506-9; discussion 509.
A large solitary amyloidoma in the cervical epidural space without bony connection and with minimal spinal cord compression and no myelopathy, as a first manifestation of disseminated amyloidosis in a multiple myeloma patient, has not been reported previously; this case is thereby distinct from the seven prior reports in the world literature, of a solitary amyloidoma of the cervical spine.
11999581
FEMALE Middle Aged
Spinal cord compression of dual etiology, multiple myeloma and spinal tuberculosis.
Yeshurun M, Laporte JP, Lesage S, Najman A.
Leuk Lymphoma. 2002;43(2):427-8.
We report for the first time a patient with spinal cord compression of dual etiology, multiple myeloma and spinal tuberculosis, treated successfully by local radiotherapy, chemotherapy and an antituberculous regimen.
11999581
FEMALE Middle Aged
Spinal cord compression of dual etiology, multiple myeloma and spinal tuberculosis.
Yeshurun M, Laporte JP, Lesage S, Najman A.
Leuk Lymphoma. 2002;43(2):427-8.
Spinal cord compression of dual etiology, multiple myeloma and spinal tuberculosis.
9836358
MALE
Spontaneous spinal epidural hematoma with spinal cord compression complicating plasma cell myeloma. A case report.
Hayem G, Deutsch E, Roux S, Palazzo E, Grossin M, Meyer O.
Spine (Phila Pa 1976). 1998;23(22):2432-5.
Spontaneous spinal epidural hematoma with spinal cord compression complicating plasma cell myeloma.
7803551
MIXED_SAMPLE Middle Aged
[Extramedullary intracranial solitary plasmocytoma. Report of 2 cases].
Rivas L, Guzman JR, Mora-La Cruz E, Cardozo J.
Invest Clin. 1994;35(3):155-67.
Multiple myeloma frequently affects the C.N.S with a high prevalence of spinal cord compression following vertebral neoplastic infiltration.