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Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Myelopathy

Total: 9

(per page)

PMID (PMCID)
30131933 (6101442)	OTHER
	Intracranial Calcification Masquerading as Hemorrhage in a Patient with Multiple Myeloma Presenting with Facial Neuropathy.
	Mullaguri N, Battineni A, Guddeti R. Cureus. 2018;10(6):e2841.
	Multiple myeloma is animmunoglobulin-producingplasma cell neoplasm that commonly affectsthebones, kidneys,thehematopoietic system, and rarelythenervous system.Peripheral nervous systeminvolvement in the form ofcranial neuropathy,radiculopathy, andpolyneuropathy are common.Compressive myelopathy constitutesthemajorityof central nervous system disorders followed by cerebrovascular disorders, intracranial plasmacytomas,andleptomeningealmyelomatosis.Cerebrovascular complicationssuch as acute ischemic stroke and transient ischemicattackarenot uncommon.
20031303	MALE	Middle Aged
	Intracranial plasmacytoma with apoplectic presentation and spontaneous intracerebral hemorrhage: Case report and review of the literature.
	Crowley RW, Sansur CA, Sheehan JP, Mandell JW, Kassell NF, Dumont AS. Clin Neurol Neurosurg. 2010;112(2):172-5.
	Involvement of the nervous system is not uncommon in patients with multiple myeloma, with polyneuropathy and myelopathy predominating.
15576117	MALE
	Multiple myeloma-associated solitary epidural amyloidoma of C2-C3 without bony connection or myelopathy: case report and review of the literature.
	Belber CJ, Graham DL. Surg Neurol. 2004;62(6):506-9; discussion 509.
	Multiple myeloma-associated solitary epidural amyloidoma of C2-C3 without bony connection or myelopathy: case report and review of the literature.
15576117	MALE
	Multiple myeloma-associated solitary epidural amyloidoma of C2-C3 without bony connection or myelopathy: case report and review of the literature.
	Belber CJ, Graham DL. Surg Neurol. 2004;62(6):506-9; discussion 509.
	A large solitary amyloidoma in the cervical epidural space without bony connection and with minimal spinal cord compression and no myelopathy, as a first manifestation of disseminated amyloidosis in a multiple myeloma patient, has not been reported previously; this case is thereby distinct from the seven prior reports in the world literature, of a solitary amyloidoma of the cervical spine.
10225602	MIXED_SAMPLE
	Vertebral plasma cell tumors in 8 dogs.
	Rusbridge C, Wheeler SJ, Lamb CR, Page RL, Carmichael S, Brearley MJ, Bjornson AP. J Vet Intern Med. 1999;13(2):126-33.
	Two dogs with solitary plasmacytomas of the spine had chemotherapy and radiotherapy: the 1st survived 4 months and was euthanized after developing radiation myelopathy; the 2nd survived 65 months before developing multiple myeloma.
1794735	MIXED_SAMPLE	Adult
	Myelopathies during the course of multiple myeloma.
	Economopoulos T, Pappa V, Panani A, Stathakis N, Dervenoulas J, Papageorgiou E, Asprou N, Raptis S. Haematologica. 1991;76(4):289-92.
	Myelopathies during the course of multiple myeloma.
1950457	OTHER	Middle Aged
	Necrotizing myelopathy associated with multiple myeloma.
	Storey E, McKelvie PA. Acta Neurol Scand. 1991;84(2):98-101.
	Necrotizing myelopathy associated with multiple myeloma.
6096963	MIXED_SAMPLE	Adult
	[Neurologic manifestations of monoclonal gammapathies].
	Uldry PA, Steck AJ, Regli F. Schweiz Med Wochenschr. 1984;114(47):1678-85.
	We have studied 8 patients with monoclonal gammopathy (2 "monoclonal gammopathies of undetermined significance" [MGUS], 2 multiple myeloma and 4 Waldenstrom's macroglobulinemia) and associated neurological complications (polyneuropathy, encephalopathy, noncompressive myelopathy).
7362492	FEMALE	Middle Aged
	Multiple vertebral hemangiomas resembling metastases with spinal cord compression.
	Zito G, Kadis GN. Arch Neurol. 1980;37(4):247-8.
	Multiple bony lesions, paravertebral mass, abnormal serum protein levels, and myelopathy suggested multiple myeloma or metastatic neoplasm.