Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Leukoencephalopathy

This term describes abnormality of the white matter of the cerebrum resulting from damage to the myelin sheaths of nerve cells.


Total: 3

                       


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PMID (PMCID)
26118258
 MALE
ASSOCIATION OF TEMPORAL LOBE INFLAMMATORY LEUKOENCEPHALOPATHY WITH TWO B CELL MALIGNANCIES.
Garzuly F, Hahn K, Ivanyi LJ, Kereskai L, Gabor V, Kovacs GG, Budka H, Kalman B.
Ideggyogy Sz. 2014;67(3-4):135-9.
Based on recent data from genomic studies, we propose that a sequential evolution of molecular pathology lead to the co-occurrence of multiple myeloma and primary central nervous system B cell lymphoma in this patient, and interpret the development of the temporal lobe leukoencephalopathy as a likely paraneoplastic complication of smoldering myeloma.
10643546
 MIXED_SAMPLE
Leukoencephalopathy in multiple myeloma: two case reports.
Lebrun C, Chanalet S, Frenay M, Chatel M.
Ann Oncol. 1999;10(12):1515-7.
We report on two patients with a very rare association of leukoencephalopathy and multiple myeloma revealed by cognitive impairment.
10643546
 MIXED_SAMPLE
Leukoencephalopathy in multiple myeloma: two case reports.
Lebrun C, Chanalet S, Frenay M, Chatel M.
Ann Oncol. 1999;10(12):1515-7.
Leukoencephalopathy in multiple myeloma: two case reports.