Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Recurrent infections

Increased susceptibility to infections.


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PMID (PMCID)
20134391
 MALE Middle Aged
Multiple myeloma presenting as recurrent sinopulmonary infections.
Kang J, Kumar A, Monteleone C.
South Med J. 2010;103(3):260-1.
The correct diagnosis of multiple myeloma can be easily overlooked, especially in a patient with recurrent infections but no other signs or symptoms typical of myeloma.
7744327
 FEMALE
[Multiple myeloma: a geriatric dilemma].
Feldman J, Yaretzky A.
Harefuah. 1995;128(4):210-2, 264, 263.
There was neither Bence-Jones protein nor hypercalcemia, nor clinical signs of multiple myeloma, such as bone pain, pathological fractures, or recurrent infections.