Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Hyponatremia

An abnormally decreased sodium concentration in the blood.


Total: 6

                       


(per page)
PMID (PMCID)
30733892
 OTHER
Bortezomib-induced hyponatremia: tolvaptan therapy permits continuation of lenalidomide, bortezomib and dexamethasone therapy in relapsed myeloma.
O'Connor-Byrne N, Glavey S, Tudor R, Murphy P, Thompson CJ, Quinn J.
Exp Hematol Oncol. 2019;8:4.
The development of hyponatremia due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) is well recognised in multiple myeloma (MM).
22073499
 FEMALE Middle Aged
Syndrome of inappropriate antidiuretic hormone due to multiple myeloma.
Abraham A, Shafi F, Iqbal M, Kollipara R, Rouf E.
Mo Med. 2011;108(5):377-9.
Although there is a plethora of literature reporting multiple myeloma induced spurious hyponatremia, our review revealed only one case report, in 1983, describing multiple myeloma induced SIADH.
22073499
 FEMALE Middle Aged
Syndrome of inappropriate antidiuretic hormone due to multiple myeloma.
Abraham A, Shafi F, Iqbal M, Kollipara R, Rouf E.
Mo Med. 2011;108(5):377-9.
Although there is a plethora of literature reporting multiple myeloma induced spurious hyponatremia, our review revealed only one case report, in 1983, describing multiple myeloma induced SIADH.
6823611
 FEMALE
Multiple myeloma and syndrome of inappropriate secretion of antidiuretic hormone.
Nanji AA.
South Med J. 1983;76(2):270.
I have described a patient with multiple myeloma who had hyponatremia probably secondary to SIADH.
645438
 MIXED_SAMPLE
Extreme hyponatremia in patients with myelomatosis: an effect of cationic paraproteins.
Bloth B, Christensson T, Mellstedt H.
Acta Med Scand. 1978;203(4):273-5.
Extreme hyponatremia in patients with myelomatosis: an effect of cationic paraproteins.
10101
 MALE Adult
Negative anion gap in a young adult with multiple myeloma.
Gumprecht T, O'Connor DT, Rearden A, Wolf PL.
Clin Chem. 1976;22(11):1920-1.
A young patient with multiple myeloma was found to have a negative anion gap, with marked asymptomatic hyponatremia.