Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Hyperchloremic metabolic acidosis



Total: 3

                      


(per page)
PMID (PMCID)
6383030
MALE Middle Aged
Hyporeninemic hypoaldosteronism in a patient with multiple myeloma.
Mehta BR, Cavallo T, Remmers AR Jr, DuBose TD Jr.
Am J Kidney Dis. 1984;4(2):175-8.
Both proximal and distal renal tubular acidification defects have been described previously in patients with multiple myeloma, but this is the first report of hyporeninemic hypoaldosteronism, hyperkalemia, and hyperchloremic metabolic acidosis in association with renal involvement in multiple myeloma.
6383030
MALE Middle Aged
Hyporeninemic hypoaldosteronism in a patient with multiple myeloma.
Mehta BR, Cavallo T, Remmers AR Jr, DuBose TD Jr.
Am J Kidney Dis. 1984;4(2):175-8.
Both proximal and distal renal tubular acidification defects have been described previously in patients with multiple myeloma, but this is the first report of hyporeninemic hypoaldosteronism, hyperkalemia, and hyperchloremic metabolic acidosis in association with renal involvement in multiple myeloma.
7224746
MALE
Distal renal tubular acidosis in multiple myeloma.
Lazar GS, Feinstein DI.
Arch Intern Med. 1981;141(5):655-6.
A patient with early multiple myeloma was initially seen with a severe hyperchloremic metabolic acidosis with a normal anion gap and a urine pH of 6.3.