Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Primary hyperparathyroidism

A type of hyperparathyroidism caused by a primary abnormality of the parathyroid glands (e.g., adenoma, carcinoma, hyperplasia). Primary hyperparathyroidism is associated with hyercalcemia.


Total: 23

                       


(per page)
PMID (PMCID)
30065055
 FEMALE Middle Aged
Acute kidney injury associated with hypercalcaemic crisis in a patient with primary hyperparathyroidism.
Sethi J, Kumar V, Rathi M, Gupta KL.
BMJ Case Rep. 2018;2018:.
Parathyroid or hypercalcaemic crisis is a rare presenting manifestation of primary hyperparathyroidism and usually seen in relation to parathyroid carcinoma and multiple myeloma.
28808512
(5538245)
 OTHER
A case of hypercalcemia with double pathology.
Abdalla A, Bachuwa G, Al Hadidi S.
J Community Hosp Intern Med Perspect. 2017;7(3):178-181.
But because all features were not fully explained by primary hyperparathyroidism, further work-up revealed multiple myeloma.
27335601
(4908746)
 OTHER
Hypercalcemia as a Cause of Kidney Failure: Case Report.
Stojceva-Taneva O, Taneva B, Selim G.
Open Access Maced J Med Sci. 2016;4(2):283-6.
He had a positive medical history for calcium-containing antacids intake and after ruling out primary hyperparathyroidism, malignancy, multiple myelomas, sarcoidosis, and thyroid dysfunction, it seemed plausible to diagnose him as having the milk-alkali syndrome.
22744630
 FEMALE Middle Aged
Oncogenic osteomalacia should be considered in hypophosphatemia, bone pain and pathological fractures.
Kaniuka-Jakubowska S, Biernat W, Lewczuk A, witkowska-Stodulska R, Sworczak K.
Endokrynol Pol. 2012;63(3):234-8.
Multiple myeloma, primary hyperparathyroidism and bone metastatic disease were excluded.
20228595
 FEMALE Middle Aged
Medical management of primary hyperparathyroidism with concomitant multiple myeloma.
Fanari Z, Kadikoy H, Haque W, Pacha O, Abdellatif A.
Intern Med. 2010;49(6):581-4.
Primary hyperparathyroidism (PHPT) and multiple myeloma (MM) are frequently observed in the adult population and can each independently lead to hypercalcemia.
18344928
 FEMALE
[Coexistence of primary hyperparathyroidism and multiple myeloma: association and rare manifestations].
Bogas M, Costa L, Araujo D.
Acta Reumatol Port. 2008;33(1):98-105.
The authors report a case of a female patient in whom the investigation of hypercalcemia and musculoskeletal manifestations led to a simultaneous diagnosis of multiple myeloma and primary hyperparathyroidism.
17475588
 MALE Middle Aged
Plasmacytoma mimicking mediastinal parathyroid tumour in a patient with primary hyperparathyroidism.
Jacob JJ, John M, Thomas M, Thomas N, Nair A.
Asian J Surg. 2007;30(2):147-50.
Many case reports have documented the coexistence of primary hyperparathyroidism and multiple myeloma.
17395337
 FEMALE
[Hypercalcemia of double origin: association of multiple myeloma and ectopic parathyroidal adenoma].
Fery-Blanco C, Prati C, Ornetti P, Bevalot J, Streit G, Toussirot E, Wendling D.
Rev Med Interne. 2007;28(7):504-6.
Multiple myeloma and primary hyperparathyroidism can be associated.
17395337
 FEMALE
[Hypercalcemia of double origin: association of multiple myeloma and ectopic parathyroidal adenoma].
Fery-Blanco C, Prati C, Ornetti P, Bevalot J, Streit G, Toussirot E, Wendling D.
Rev Med Interne. 2007;28(7):504-6.
Multiple myeloma and primary hyperparathyroidism are two causes of hypercalcemia.
15760779
 FEMALE
Multiple myeloma presenting with recurrent hypercalcemia in a patient with a history of primary hyperparathyroidism: report of case and review of literature.
Khandwala HM, Boctor MA.
Endocr Pract. 2004;10(4):345-7.
To report a case of primary hyperparathyroidism (PHPT) that presented with recurrent hypercalcemia due to multiple myeloma after successful parathyroidectomy.
9152621
 FEMALE
A case of primary hyperparathyroidism accompanying multiple myeloma.
Otsuka F, Hayakawa N, Ogura T, Kataoka H, Kawashima M, Mimura Y, Yamauchi T, Kashihara N, Kageyama J, Makino H.
Endocr J. 1997;44(1):105-9.
A case of primary hyperparathyroidism accompanying multiple myeloma.
7891547
 MIXED_SAMPLE Adult
Milk-alkali syndrome associated with calcium carbonate consumption. Report of 7 patients with parathyroid hormone levels and an estimate of prevalence among patients hospitalized with hypercalcemia.
Beall DP, Scofield RH.
Medicine (Baltimore). 1995;74(2):89-96.
Only primary hyperparathyroidism and hypercalcemia of malignancy (excluding multiple myeloma) are more common.
8563101
 FEMALE
Primary hyperparathyroidism associated with multiple myeloma.
Goto S, Yoshioka M, Nagai K, Abe A, Murakawa E, Yamazaki N, Koyama T, Sekiya M.
Intern Med. 1995;34(10):988-91.
In spite of the frequent association of hypercalcemia with malignant disease and the relative frequency of primary hyperparathyroidism as a cause of hypercalcemia, primary hyperparathyroidism accompanied by multiple myeloma has been considered in only a limited number of reports.
8563101
 FEMALE
Primary hyperparathyroidism associated with multiple myeloma.
Goto S, Yoshioka M, Nagai K, Abe A, Murakawa E, Yamazaki N, Koyama T, Sekiya M.
Intern Med. 1995;34(10):988-91.
In spite of the frequent association of hypercalcemia with malignant disease and the relative frequency of primary hyperparathyroidism as a cause of hypercalcemia, primary hyperparathyroidism accompanied by multiple myeloma has been considered in only a limited number of reports.
8563101
 FEMALE
Primary hyperparathyroidism associated with multiple myeloma.
Goto S, Yoshioka M, Nagai K, Abe A, Murakawa E, Yamazaki N, Koyama T, Sekiya M.
Intern Med. 1995;34(10):988-91.
Primary hyperparathyroidism associated with multiple myeloma.
8108668
 FEMALE
Coexisting kappa light chain multiple myeloma and primary hyperparathyroidism.
Toussirot E, Bille F, Henry JF, Acquaviva PC.
Scand J Rheumatol. 1994;23(1):49-50.
Coexisting kappa light chain multiple myeloma and primary hyperparathyroidism.
1856101
 MIXED_SAMPLE Middle Aged
Primary hyperparathyroidism and monoclonal gammopathy.
Rao DS, Antonelli R, Kane KR, Kuhn JE, Hetnal C.
Henry Ford Hosp Med J. 1991;39(1):41-4.
Another patient with primary hyperparathyroidism also had multiple myeloma and was in remission for 12 years.
2683649
 MALE Middle Aged
[Multiple myeloma in a patient with primary hyperparathyroidism].
Katayama Y, Matsuda H, Katoh Y, Kohri K, Iguchi M, Kurita T, Fujii R.
Hinyokika Kiyo. 1989;35(8):1369-72.
[Multiple myeloma in a patient with primary hyperparathyroidism].
6486991
 FEMALE Middle Aged
Primary hyperparathyroidism complicated by multiple myeloma.
Hoelzer DR, Silverberg AB.
Arch Intern Med. 1984;144(10):2069-71.
A patient with primary hyperparathyroidism and multiple myeloma did not have roentgenographic evidence of either disease, yet there was biochemical evidence for both diseases.
6486991
 FEMALE Middle Aged
Primary hyperparathyroidism complicated by multiple myeloma.
Hoelzer DR, Silverberg AB.
Arch Intern Med. 1984;144(10):2069-71.
Primary hyperparathyroidism complicated by multiple myeloma.