Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Chronic infection

Presence of a protracted or persistent infection by a pathogen potentially related to an underlying abnormality of the immune system that is not able to clear the infection.

Total: 4

(per page)

PMID (PMCID)
23278475	FEMALE
	Multiple myeloma in a dog with multiple concurrent infectious diseases and persistent polyclonal gammopathy.
	Geigy C, Riond B, Bley CR, Grest P, Kircher P, Lutz H. Vet Clin Pathol. 2013;42(1):47-54.
	This is a rare report of a dog with suspected multiple myeloma and a history of multiple chronic infectious diseases, suggesting that chronic infection and uncontrolled long-term stimulation of the immune system could contribute to the pathogenesis of multiple myeloma.
23278475	FEMALE
	Multiple myeloma in a dog with multiple concurrent infectious diseases and persistent polyclonal gammopathy.
	Geigy C, Riond B, Bley CR, Grest P, Kircher P, Lutz H. Vet Clin Pathol. 2013;42(1):47-54.
	This is a rare report of a dog with suspected multiple myeloma and a history of multiple chronic infectious diseases, suggesting that chronic infection and uncontrolled long-term stimulation of the immune system could contribute to the pathogenesis of multiple myeloma.
15657729	MIXED_SAMPLE	Middle Aged
	[Rare types of vasculitis as markers of plasmocytoma].
	Marini A, Fenk R, Plettenberg H, Ruzicka T, Haas R, Hengge UR. Hautarzt. 2006;57(2):137-43.
	Common etiological factors include bacterial, viral or drug antigens, chronic infections (hepatitis B and C), non-Hodgkin lymphomas (monoclonal gammopathy, multiple myeloma), leukemia (hairy cell leukemia), and tumors (bronchial, breast, and gastric cancer) and also connective tissue disorders.
6699975	MALE	Adult
	Longitudinal studies of prostatic fluid immunoglobulin in men with bacterial prostatitis.
	Fowler JE Jr, Mariano M. J Urol. 1984;131(2):363-9.
	Three men with bacterial prostatitis, including 2 otherwise healthy men with chronic infections and 1 man with IgG multiple myeloma and an acute infection, were studied.