Multiple myeloma

Multiple myeloma (MM) is a malignant tumor of plasma cell characterized by overproduction of abnormal plasma cells in the bone marrow and skeletal destruction. The clinical features are bone pain, renal impairment, immunodeficiency, anemia and presence of abnormal immunoglobulins (Ig).

Granulocytosis

An increased count of granulocytes in the peripheral blood circulation.


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PMID (PMCID)
9503469
 MALE Middle Aged
A case of multiple myeloma producing granulocyte colony-stimulating factor.
Usuda H, Naito M, Ohyach K, Iizumi T.
Pathol Int. 1997;47(12):866-9.
A case of multiple myeloma (IgA-lambda) with marked granulocytosis, which measured up to 9.9 x 10(4)/mm3, is described.