Congenital varicella syndrome

Fetal varicella syndrome (CVS) is an acquired developmental anomaly syndrome characterized by skin, neurological, ocular, limbs and growth defects secondary to maternal Varicella-Zoster Virus (VZV) infection.

Microcephaly

Head circumference below 2 standard deviations below the mean for age and gender.


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PMID (PMCID)
1743417
FEMALE Infant
Severe microcephaly associated with congenital varicella infection.
Scheffer IE, Baraitser M, Brett EM.
Dev Med Child Neurol. 1991;33(10):916-20.
A case of second-trimester congenital varicella infection, in association with isolated microcephaly and severe brain damage, is reported, and cases of classical congenital varicella syndrome are compared on a clinical and immunological basis.