Satoyoshi syndrome

Satoyoshi syndrome is a rare, multisystemic autoimmune disease mainly characterized by intermittent painful muscle spasms, alopecia (totalis or universalis in most cases) and long-lasting diarrhea that could lead to malnutrition, growth retardation, and amenorrhea. Secondary bone deformities and various endocrine anomalies may also be associated. Antinuclear antibodies are reported in many cases.

Muscle spasm

Sudden and involuntary contractions of one or more muscles.


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(per page)
PMID (PMCID)
27011647
(4782532)
 OTHER
Adult-onset Satoyoshi syndrome and response to plasmapheresis.
Aghoram R, Srijithesh PR, Kannoth S.
Ann Indian Acad Neurol. 2016;19(1):131-3.
Satoyoshi syndrome is a rare disease characterized by alopecia, recurrent muscle spasms, diarrhea, and skeletal abnormalities Adult-onset disease is reported only in five patients.
22612551
 FEMALE Child
Satoyoshi syndrome: a cause of alopecia universalis in association with neurologic and bony abnormalities.
Merino de Paz N, Rodriguez-Martin M, Contreras Ferrer P, Eliche MP, Noda Cabrera A.
Pediatr Dermatol. 2013;30(3):e22-4.
Satoyoshi syndrome is a rare multisystemic disorder characterized by alopecia, diarrhea, muscle spasms, osseous abnormalities, and endocrinopathies.
22100320
 FEMALE Young Adult
Satoyoshi's syndrome related muscle spasms: functional study.
Pardal-Fernandez JM, Solera-Santos J, Iniesta-Lopez I, Rodriguez-Vazquez M.
Rev Neurol (Paris). 2012;168(3):291-5.
Satoyoshi syndrome is a rare disease presumed to be immunologically mediated, characterized by muscle spasms, alopecia and diarrhea.
21301038
 MIXED_SAMPLE Young Adult
[Satoyoshi syndrome].
Satoyoshi E.
Brain Nerve. 2011;63(2):141-6.
Satoyoshi syndrome is a rare disorder of unknown case characterized by progressive painful intermittent muscle spasms, alopecia, malabsorption amenorrhea and skeletal abnormalities mimicking a skeletal dysplasia.
19623421
 FEMALE
[Satoyoshi syndrome: report of one case].
Castiglioni C, Diaz A, Moenne K, Mericq V, Salvador F, Hernandez C.
Rev Med Chil. 2009;137(4):542-6.
Satoyoshi syndrome is a rare multisystemic disease of presumed autoimmune etiology characterized by progressive painful intermittent muscle spasms, diarrhea frequently associated with malabsorption, alopecia, skeletal abnormalities and endocrine disorders with a poor long-term prognosis due to early crippling.
15069249
 FEMALE Adult
Satoyoshi syndrome.
Ashalatha R, Kishore A, Sarada C, Nair MD.
Neurol India. 2004;52(1):94-5.
Satoyoshi syndrome (Komuragaeri disease) is a rare disorder of presumed autoimmune etiology, characterized by painful muscle spasms, alopecia, diarrhea, endocrinopathy with amenorrhoea and secondary skeletal abnormalities.
15069249
 FEMALE Adult
Satoyoshi syndrome.
Ashalatha R, Kishore A, Sarada C, Nair MD.
Neurol India. 2004;52(1):94-5.
Satoyoshi syndrome (Komuragaeri disease) is a rare disorder of presumed autoimmune etiology, characterized by painful muscle spasms, alopecia, diarrhea, endocrinopathy with amenorrhoea and secondary skeletal abnormalities.
14601924
 MALE
A case of Satoyoshi syndrome: a multisystem disorder.
Kamat D, Petry L, Berry S.
Clin Pediatr (Phila). 2003;42(8):745-8.
This patient had alopecia, muscle spasms, and skeletal abnormalities, which are three of the most common clinical features of Satoyoshi syndrome.
12710092
 MALE
[A case of Satoyoshi syndrome complicating marginal gingivitis of the mandible and dislocation of the temporomandibular joint].
Matsumura T, Yokoe M, Shinno S.
Rinsho Shinkeigaku. 2002;42(9):889-91.
Satoyoshi syndrome is a very rare disorder, characterized by progressive painful intermittent muscle spasms beginning in adolescence.
9804090
 FEMALE
Satoyoshi's syndrome in an adult: a review of the literature of adult onset cases.
Ikeda K, Satoyoshi E, Kinoshita M, Wakata N, Iwasaki Y.
Intern Med. 1998;37(9):784-7.
Satoyoshi syndrome consists of painful intermittent muscle spasms, alopecia and diarrhea.
9868307
 MALE Adult
[A case of Satoyoshi syndrome with symptoms resembling neuroleptic malignant syndrome].
Adachi H, Riku S, Fujishiro K, Kuru S.
Rinsho Shinkeigaku. 1998;38(7):637-40.
Satoyoshi syndrome is a rare neurological disorder of unknown etiology characterized by progressive muscle spasms, alopecia, diarrhea and skeletal abnormalities.
9133353
 FEMALE Adult
Radiological and orthopedic abnormalities in Satoyoshi syndrome.
Haymon M, Willis RB, Ehlayel MS, Lacassie Y.
Pediatr Radiol. 1997;27(5):415-8.
Satoyoshi syndrome is a rare disorder of unknown etiology characterized by progressive, painful intermittent muscle spasms, severe skeletal abnormalities mimicking a skeletal dysplasia, malabsorption, alopecia, and amenorrhea.
8139588
 MALE Middle Aged
Masticatory muscle spasm in a non-Japanese patient with Satoyoshi syndrome successfully treated with botulinum toxin.
Merello M, Garcia H, Nogues M, Leiguarda R.
Mov Disord. 1994;9(1):104-5.
Masticatory muscle spasm in a non-Japanese patient with Satoyoshi syndrome successfully treated with botulinum toxin.
2044311
 FEMALE
[A case of generalized komuragaeri disease (Satoyoshi disease) treated with glucocorticoid].
Yamagata T, Miyao M, Momoi M, Matsumoto S, Yanagisawa M.
Rinsho Shinkeigaku. 1991;31(1):79-83.
Generalized komuragaeri disease (Satoyoshi disease) is a rare disorder of unknown etiology, characterized by painful muscle spasms, alopecia, diarrhea and various endocrine disorders.
6524180
 FEMALE
[Positive therapeutic effect of diacarb in the syndrome of progressive muscle spasms, alopecia and diarrhea (Satoyoshi syndrome)].
Aver'ianov IuN, Vodolagin VD, Logunova LV, Levina LIa.
Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(11):1623-7.
[Positive therapeutic effect of diacarb in the syndrome of progressive muscle spasms, alopecia and diarrhea (Satoyoshi syndrome)].