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Autoimmune lymphoproliferative syndrome

A rare, inherited disorder characterized by non-malignant lymphoproliferation, multilineage cytopenias, and a lifelong increased risk of Hodgkin's and non-Hodgkin's lymphoma.

Jaundice

Yellow pigmentation of the skin due to bilirubin, which in turn is the result of increased bilirubin concentration in the bloodstream.

Total: 1

(per page)

PMID (PMCID)
17638424	MALE	Infant, Newborn
	Autoimmune lymphoproliferative syndrome (ALPS): a case with congenital onset.
	Kahwash SB, Fung B, Savelli S, Bleesing JJ, Qualman SJ. Pediatr Dev Pathol. 2007;10(4):315-9.
	We describe a case of autoimmune lymphoproliferative syndrome (ALPS), which is very unusual with regard to a clinical onset soon after birth, and a clinical picture dominated by splenomegaly, jaundice, and consumptive peripheral blood cytopenias, with minimal lymphadenopathy.