Trisomy 13

Trisomy 13 is a chromosomal anomaly caused by the presence of an extra chromosome 13 and is characterized by brain malformations (holoprosencephaly), facial dysmorphism, ocular anomalies, postaxial polydactyly, visceral malformations (cardiopathy) and severe psychomotor retardation.

Anemia

A reduction in erythrocytes volume or hemoglobin concentration.


Total: 1

                       


(per page)
PMID (PMCID)
9236512
 FEMALE Adult
Induction of a hematological and cytogenetic remission in a patient with a myelodysplastic syndrome secondary to Fanconi's anemia employing the S-HAM regimen.
Verbeek W, Haase D, Schoch C, Hiddemann W, Wormann B.
Ann Hematol. 1997;74(6):275-7.
We report on a patient with Fanconi's anemia (FA) who developed a myelodysplastic syndrome (RAEB-T) with complex karyotypic abnormalities (trp 1q23q42, monosomy 20, trisomy 13) at the age of 28.