Truncus arteriosus

Truncus arteriosus (TA) is a rare congenital cardiovascular anomaly characterized by a single arterial trunk arising from the heart by means of a single semilunar valve (<I>i.e.</I> truncal valve). Pulmonary arteries originate from the common arterial trunk distal to the coronary arteries and proximal to the first brachiocephalic branch of the aortic arch. TA typically overrides a large outlet ventricular septal defect (VSD). The intracardiac anatomy usually displays situs solitus and atrioventricular (AV) concordance.

Asplenia

Absence (aplasia) of the spleen.


Total: 3

                       


(per page)
PMID (PMCID)
11146459
 MIXED_SAMPLE Infant, Newborn
Variability in the phenotypic expression of fryns syndrome: A report of two sibships.
Ramsing M, Gillessen-Kaesbach G, Holzgreve W, Fritz B, Rehder H.
Am J Med Genet. 2000;95(5):415-24.
The two affected fetuses of family 1 showed severe craniofacial anomalies with bilateral cleft lip and palate, acral hypoplasia, postaxial oligodactyly, persistent truncus arteriosus, and interrupted aortic arch, asplenia sequence, and complex central nervous system midline malformations.
1876522
 MALE Infant, Newborn
Associated occurrence of persistent truncus arteriosus and asplenia.
Gumbiner CH, McManus BM, Latson LA.
Pediatr Cardiol. 1991;12(3):192-5.
An infant with persistent truncus arteriosus associated with splenic agenesis and the asplenia syndrome is reported, including clinical, echocardiographic and autopsy findings.
1876522
 MALE Infant, Newborn
Associated occurrence of persistent truncus arteriosus and asplenia.
Gumbiner CH, McManus BM, Latson LA.
Pediatr Cardiol. 1991;12(3):192-5.
Associated occurrence of persistent truncus arteriosus and asplenia.