Familial Mediterranean fever

Familial Mediterranean fever (FMF) is an autoinflammatory disorder characterized by recurrent short episodes of fever and serositis resulting in pain in the abdomen, chest, joints and muscles.

Abdominal pain

An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) and perceived to originate in the abdomen.


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PMID (PMCID)
28255474
(5306980)
 OTHER
A Case of Eosinophilic Esophagitis Accompanying Familial Mediterranean Fever.
Rohani P, Najafi Sani M, Ahmadi M, Ziaee V.
Case Rep Gastrointest Med. 2017;2017:6863921.
Because of continuing abdominal pain after treatment of eosinophilic esophagitis, the episodic nature of disease, and the presence of fever with pain, screening for familial Mediterranean fever mutation was performed and the patient was found to be heterozygote for Mediterranean fever.
27181238
 FEMALE Adult
A case of familial Mediterranean fever who complained of periodic fever and abdominal pain diagnosed by MEFV gene analysis.
Ogita C, Matsui K, Kisida D, Kakudou M, Yazaki M, Nakamura A, Azuma K, Tsuboi K, Abe T, Yokoyama Y, Furukawa T, Maruoka M, Tamura M, Yoshikawa T, Saito A, Nishioka A, Sekiguchi M, Azuma N, Kitano M, Tsunoda S, Hashimoto-Tamaoki T, Sano H.
Nihon Rinsho Meneki Gakkai Kaishi. 2016;39(1):72-7.
A case of familial Mediterranean fever who complained of periodic fever and abdominal pain diagnosed by MEFV gene analysis.
26923897
 MALE
Newly Diagnosed Crohn's Disease in Patient with Familial Mediterranean Fever.
Akar T, Dindar G, Malkoc D, Karagozoglu K, Klavuz B, Ustundag Y.
Arch Iran Med. 2016;19(3):225-8.
Similarly, familial Mediterranean fever disease and Crohn's disease have the same clinical features in terms of chronic abdominal pain, and inflammatory properties of these diseases.
26554556
(4641426)
 MALE
Intestinal malrotation as a misdiagnosis of pediatric colchicine resistant familial Mediterranean fever.
Heshin-Bekenstein M, Hashkes PJ.
Pediatr Rheumatol Online J. 2015;13(1):45.
Familial Mediterranean fever (FMF) is a disorder characterized by recurrent attacks of fever and serosal inflammation, particularly abdominal pain.
25261084
(4182779)
 MALE Adult
Familial Mediterranean fever in which Crohn's disease was suspected: a case report.
Matsumoto S, Urayoshi S, Yoshida Y.
BMC Res Notes. 2014;7:678.
Although Crohn's disease may be considered first in the differential diagnosis of young patients presenting with periodic fever, abdominal pain and diarrhea, the possibility of familial Mediterranean fever should also be borne in mind.
25332561
 OTHER
The coincidence of familial mediterranean Fever and hypereosinophilia in a patient with hereditary elliptocytosis.
Keklik M, Unal A, Sivgin S, Kontas O, Eroglu E, Yilmaz S, Kaynar L, Eser B, Cetin M.
Indian J Hematol Blood Transfus. 2014;30(Suppl 1):138-41.
Familial Mediterranean fever (FMF) is a genetic disease with autosomal inheritance characterized by recurrent fever, abdominal pain, and serositis attacks.
22505824
(3325009)
 OTHER
38-year-old woman with recurrent abdominal pain, but no fever.
Iwata K, Toma T, Yachie A.
Int J Gen Med. 2012;5:265-8.
After ruling out common causes of recurrent abdominal pain, familial Mediterranean fever (FMF) was considered as a potential diagnosis.
22842301
 OTHER
Familial Mediterranean fever without cardinal symptoms and role of genetic screening.
Ulas T, Buyukhatipoglu H, Bes C, Dal MS, Hacbekiroglu I, Apucu HG, Borlu F.
Reumatismo. 2012;64(3):172-4.
Herein, we present a case of 34-year-old man with incomplete abdominal pain episode of familial mediterranean fever limited to the epigastrum and had no cardinals symptoms of this disease.
20890251
 MALE Adult
MEFV gene mutations in a patient with eosinophilic gastroenteritis.
Kocak G, Kocak E, Yilmaz SR, Koklu S, Duranay M, Yalcin F, Albayrak Y.
South Med J. 2010;103(11):1170-2.
A 39-year-old man who was followed up with the diagnosis of familial Mediterranean fever (FMF) was admitted to our clinic with diarrhea, abdominal pain, and weight loss.
20203446
 MALE Adult
[A Japanese family with adult-onset familial Mediterranean fever and periodic episodes of high fever and abdominal pain].
Araki H, Onogi F, Ibuka T, Moriwaki H.
Nihon Shokakibyo Gakkai Zasshi. 2010;107(3):427-31.
[A Japanese family with adult-onset familial Mediterranean fever and periodic episodes of high fever and abdominal pain].
19744393
 MALE Adult
[Recurrent pericardial effusion due to familiar Mediterranean fever].
Halabe-Cherem J, Hamui-Sutton A, Cohen-Cohen S, Sacal-Dumani E, Shuchleib-Cung A, Nellen-Hummel H, Rabago-Arredondo J.
Rev Med Inst Mex Seguro Soc. 2009;47(2):211-4.
It can also be related to familial Mediterranean fever, an autosomic recessive inflammatory disease, characterized by fever, abdominal pain, and pleuritis mainly seen in persons from the Mediterranean area.
16570202
 MALE
Renal amyloidosis in a child with sickle cell anemia.
Simsek B, Bayazit AK, Ergin M, Soran M, Dursun H, Kilinc Y.
Pediatr Nephrol. 2006;21(6):877-9.
He had neither a family history of familial Mediterranean fever (FMF) nor any complaint of recurrent abdominal pain, arthritis, and fever, but frequent painful vaso-occlusive crises.
17062615
 MIXED_SAMPLE Adult
Spinal cord stimulation for relief of abdominal pain in two patients with familial Mediterranean fever.
Kapur S, Mutagi H, Raphael J.
Br J Anaesth. 2006;97(6):866-8.
Familial Mediterranean fever is a hereditary disease characterized by recurrent attacks of fever and serosal inflammation that commonly presents as severe abdominal pain.
16328089
 MALE Adult
Sustained, progressive, nonresolving abdominal pain: a previously undescribed clinical presentation of familial Mediterranean fever.
Radisic M, Santamarina J, Froment R.
Clin Rheumatol. 2006;25(6):914-6.
Sustained, progressive, nonresolving abdominal pain: a previously undescribed clinical presentation of familial Mediterranean fever.
16841591
 MALE Middle Aged
[Intestinal perforation caused by tuberculosis in a kidney transplant patient who was extensively evaluated for tuberculosis prior to transplant].
Rendering H, Zijlstra JG, van Son WJ, de Maar EF, Manson WL, van der Werf TS.
Ned Tijdschr Geneeskd. 2006;150(25):1407-12.
The patient had presented at the emergency department repeatedly with abdominal pain that was attributed to the familial Mediterranean fever.
15833688
 MALE Adult
Familial Mediterranean fever--a not so unusual cause of abdominal pain.
Simon A, van der Meer JW, Drenth JP.
Best Pract Res Clin Gastroenterol. 2005;19(2):199-213.
Familial Mediterranean fever--a not so unusual cause of abdominal pain.
15801080
 MALE Adult
A case of recurrent pancreatitis due to hyperlipidemia misdiagnosed as familial Mediterranean fever.
Birlik M, Demir T, Zeybel M, Akar S, Onen F, Comlekci A, Tunca M, Akkoc N.
Clin Rheumatol. 2004;23(6):559-61.
Familial Mediterranean fever (FMF) is prevalent among Arabic, Turkish, Armenian, and Jewish people and it must always be considered in the differential diagnosis of patients from these ethnic groups presenting with recurrent abdominal pain with fever.
15015067
 FEMALE Child
Variable expression of vasculitis in siblings with familial Mediterranean fever.
Lange-Sperandio B, Mohring K, Gutzler F, Mehls O.
Pediatr Nephrol. 2004;19(5):539-43.
Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by recurrent and self-limited attacks of serosal inflammation with abdominal pain, chest pain, and arthritis usually accompanied by fever.
12811232
 FEMALE Adult
Acute vasculitis with multiorgan involvement in a patient with familial Mediterranean fever.
Braun E, Schapira D, Guralnik L, Azzam ZS.
Am J Med Sci. 2003;325(6):363-4.
We report a rare case of a patient with long-standing familial Mediterranean fever who presented with sudden onset of dyspnea, abdominal pain, and cutaneous manifestations.
15048606
 FEMALE Adult
Familial Mediterranean fever with massive recurrent ascites: a case report.
Cekin AH, Dalbudak N, Kunefeci G, Gur G, Boyacioglu S.
Turk J Gastroenterol. 2003;14(4):276-9.
Since she had a history of attacks of abdominal pain in her childhood, she was screened for mutations causing familial Mediterranean fever and was found to be homozygous for M694V.