Weill-Marchesani syndrome

Weill-Marchesani syndrome (WMS) is a rare condition characterized by short stature, brachydactyly, joint stiffness, and characteristic eye abnormalities including microspherophakia, ectopia of the lens, severe myopia, and glaucoma.

Glaucoma

Glaucoma refers loss of retinal ganglion cells in a characteristic pattern of optic neuropathy usually associated with increased intraocular pressure.


Total: 29

                       


(per page)
PMID (PMCID)
31114122
 MALE Adult
Fibrin Glue-Assisted Intraocular Lens Fixation in Weill-Marchesani Syndrome.
Kalamkar C, Radke NV, Mukherjee A, Radke SN.
Middle East Afr J Ophthalmol. 2019;26(1):33-36.
Glued IOL implantation is an effective method to visually rehabilitate and control glaucoma in patients with Weill Marchesani Syndrome.
31114122
 MALE Adult
Fibrin Glue-Assisted Intraocular Lens Fixation in Weill-Marchesani Syndrome.
Kalamkar C, Radke NV, Mukherjee A, Radke SN.
Middle East Afr J Ophthalmol. 2019;26(1):33-36.
To report visual and intraocular pressure (IOP) outcomes of 4 eyes in 2 patients with Weill Marchesani Syndrome having ocular fearures of spherophakia and secondary glaucoma who underwent fibrin glue assisted intrascleral fixation of intraocular lens (IOL).
30380740
(6266624)
 OTHER
Delineation of Novel Compound Heterozygous Variants in LTBP2 Associated with Juvenile Open Angle Glaucoma.
Saeedi O, Yousaf S, Tsai J, Palmer K, Riazuddin S, Ahmed ZM.
Genes (Basel). 2018;9(11):.
Mutations in LTBP2 are known to cause the Weill-Marchesani syndrome and a Weill-Marchesani-like syndrome, which include glaucoma in their clinical presentation.
26695613
 MIXED_SAMPLE Infant
A new combined surgical approach in a patient with microspherophakia and developmental iridocorneal angle anomaly.
Satana B, Altan C, Basarir B, Alkin Z, Yilmaz OF.
Nepal J Ophthalmol. 2015;7(1):85-9.
We report ocular findings of a 1-year-old girl who was diagnosed with Weill-Marchesani syndrome with a positive family history of glaucoma in her cousins and glaucoma with anterior segment dysgenesis in her older brother.
26695613
 MIXED_SAMPLE Infant
A new combined surgical approach in a patient with microspherophakia and developmental iridocorneal angle anomaly.
Satana B, Altan C, Basarir B, Alkin Z, Yilmaz OF.
Nepal J Ophthalmol. 2015;7(1):85-9.
We report ocular findings of a 1-year-old girl who was diagnosed with Weill-Marchesani syndrome with a positive family history of glaucoma in her cousins and glaucoma with anterior segment dysgenesis in her older brother.
25571963
(4298062)
 FEMALE Adult
Weill-Marchesani syndrome with advanced glaucoma and corneal endothelial dysfunction: a case report and literature review.
Guo H, Wu X, Cai K, Qiao Z.
BMC Ophthalmol. 2015;15:3.
Advanced glaucoma in Weill-Marchesani syndrome should be treated with combined glaucoma surgery and lens extraction.
25571963
(4298062)
 FEMALE Adult
Weill-Marchesani syndrome with advanced glaucoma and corneal endothelial dysfunction: a case report and literature review.
Guo H, Wu X, Cai K, Qiao Z.
BMC Ophthalmol. 2015;15:3.
Advanced glaucoma in Weill-Marchesani syndrome should be treated with combined glaucoma surgery and lens extraction.
25571963
(4298062)
 FEMALE Adult
Weill-Marchesani syndrome with advanced glaucoma and corneal endothelial dysfunction: a case report and literature review.
Guo H, Wu X, Cai K, Qiao Z.
BMC Ophthalmol. 2015;15:3.
Weill-Marchesani syndrome could be diagnosed by microspherophakia, high myopia, secondary glaucoma, and systemic abnormalities such as brachymorphia and brachydactyly.
25571963
(4298062)
 FEMALE Adult
Weill-Marchesani syndrome with advanced glaucoma and corneal endothelial dysfunction: a case report and literature review.
Guo H, Wu X, Cai K, Qiao Z.
BMC Ophthalmol. 2015;15:3.
To report the diagnostic features and management strategy of a rare case of Weill-Marchesani syndrome with advanced glaucoma and corneal endothelial dysfunction.
25571963
(4298062)
 FEMALE Adult
Weill-Marchesani syndrome with advanced glaucoma and corneal endothelial dysfunction: a case report and literature review.
Guo H, Wu X, Cai K, Qiao Z.
BMC Ophthalmol. 2015;15:3.
Weill-Marchesani syndrome with advanced glaucoma and corneal endothelial dysfunction: a case report and literature review.
16427698
 MIXED_SAMPLE Child
Angle closure in highly myopic eyes.
Barkana Y, Shihadeh W, Oliveira C, Tello C, Liebmann JM, Ritch R.
Ophthalmology. 2006;113(2):247-54.
Angle-closure diagnoses included primary pupillary block (9 patients), pupillary block in an eye with keratoconus (1 patient), pupillary block secondary to a pupillary membrane associated with retinopathy of prematurity (1 patient), plateau iris configuration and syndrome (3 patients), phacomorphic glaucoma in Weill-Marchesani syndrome (2 patients), malignant glaucoma secondary to a scleral buckle (2 patients), miotic-induced angle closure (1 patient), and Marfan syndrome (1 patient).
16427698
 MIXED_SAMPLE Child
Angle closure in highly myopic eyes.
Barkana Y, Shihadeh W, Oliveira C, Tello C, Liebmann JM, Ritch R.
Ophthalmology. 2006;113(2):247-54.
Angle-closure diagnoses included primary pupillary block (9 patients), pupillary block in an eye with keratoconus (1 patient), pupillary block secondary to a pupillary membrane associated with retinopathy of prematurity (1 patient), plateau iris configuration and syndrome (3 patients), phacomorphic glaucoma in Weill-Marchesani syndrome (2 patients), malignant glaucoma secondary to a scleral buckle (2 patients), miotic-induced angle closure (1 patient), and Marfan syndrome (1 patient).
16633042
 MALE Adult
Long-term complications of iris-claw phakic intraocular lens implantation in Weill-Marchesani syndrome.
Burakgazi AZ, Ozbek Z, Rapuano CJ, Rhee DJ.
Cornea. 2006;25(3):361-3.
Based on our findings of short stature, shortened and thickened fingers, relatively normal axial length, microspherophakia, high myopia, and glaucoma, we diagnosed the patient with Weill-Marchesani syndrome.
16494613
 MALE
Weill-Marchesani syndrome and secondary glaucoma associated with ectopia lentis.
Chu BS.
Clin Exp Optom. 2006;89(2):95-9.
Weill-Marchesani syndrome and secondary glaucoma associated with ectopia lentis.
12770659
 MALE Adult
Airway management of a patient with Weill-Marchesani syndrome.
Karabiyik L.
J Clin Anesth. 2003;15(3):214-6.
Weill-Marchesani syndrome is a genetically determined rare systemic connective tissue disorder consisting of brachymorphy, brachydactyly, aortic stenosis, and ophthalmologic abnormalities, such as ectopia lentis, microspherophakia, and secondary glaucoma.
12648208
 MALE Adult
Anesthetic management of a patient with Weill-Marchesani syndrome.
Dal D, Sahin A, Aypar U.
Acta Anaesthesiol Scand. 2003;47(3):369-70.
Weill-Marchesani syndrome is characterized by short stature, brachydactylyl, myopia, microspherophakia, lens dislocation, glaucoma, joint stiffness, restricted articular movements and facial features.
12098811
 FEMALE Adult
[Weill-Marchesani syndrome. Late athalamia following antiglaucomatous surgery].
Maquet Dusart JA, Dios Castro E.
Arch Soc Esp Oftalmol. 2002;77(7):385-7.
A case of a patient with Weill-Marchesani syndrome who developed a secondary glaucoma due to synechiae in both eyes is described.
11712631
 FEMALE Adult
Uncontrolled glaucoma secondary to an arteriovenous malformation in a Weill-Marchesani patient.
Derose CJ, Jeffrey A.
Optometry. 2001;72(10):641-8.
The patient demonstrates the known clinical signs of Weill-Marchesani syndrome: short stature, microspherophakia, lens subluxation, and secondary glaucoma.
11712631
 FEMALE Adult
Uncontrolled glaucoma secondary to an arteriovenous malformation in a Weill-Marchesani patient.
Derose CJ, Jeffrey A.
Optometry. 2001;72(10):641-8.
The Weill-Marchesani syndrome may be partially responsible for the glaucoma.
8913132
 FEMALE
Weill-Marchesani syndrome complicated by secondary glaucoma. Case management with surgical lens extraction.
Taylor JN.
Aust N Z J Ophthalmol. 1996;24(3):275-8.
A case of the rare Weill-Marchesani syndrome is presented with characteristic spherophakia, lenticular myopia and secondary glaucoma.