Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a systemic disease associated with the proliferation and accumulation (usually in granulomas) of Langerhans cells in various tissues.

Amenorrhea

Absence of menses for an interval of time equivalent to a total of more than (or equal to) 3 previous cycles or 6 months.


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PMID (PMCID)
8434175
 FEMALE Adult
[A histiocytosis X without histological findings: a new entity of histiocytosis X].
Hayashi Y, Hashida K, Takaoka Y, Mise H, Nishikawa T, Takada K, Kanemitsu N, Itoh T, Matsumoto H, Ueda N.
Kokyu To Junkan. 1993;41(2):171-4.
Histiocytosis X often combines pneumothorax, diabetes insipidus, amenorrhea and an abnormal radiograph of the chest.