Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a systemic disease associated with the proliferation and accumulation (usually in granulomas) of Langerhans cells in various tissues.

Diabetes insipidus

A state of excessive water intake and hypotonic (dilute) polyuria. Diabetes insipidus may be due to failure of vasopressin (AVP) release (central or neurogenic diabetes insipidus) or to a failure of the kidney to respond to AVP (nephrogenic diabetes insipidus).


Total: 60

                       


(per page)
PMID (PMCID)
28360976
(5355761)
 OTHER
Langerhans cell histiocytosis masquerading as acute appendicitis: Case report and review.
Karimzada MM, Matthews MN, French SW, DeUgarte D, Kim DY.
World J Gastrointest Endosc. 2017;9(3):139-144.
Langerhans cell histiocytosis (LCH) is a rare syndrome characterized by unifocal, multifocal unisystem, or disseminated/multi-system disease that commonly involves the bone, skin, lymph nodes, pituitary, or sometimes lung (almost exclusively in smokers) causing a variety of symptoms from rashes and bone lesions to diabetes insipidus or pulmonary infiltrates.
27920713
(5121570)
 OTHER
Late-Onset Langerhans Cell Histiocytosis with Cerebellar Ataxia as an Initial Symptom.
Pyun JM, Park H, Moon KC, Jeon B.
Case Rep Neurol. 2016;8(3):218-223.
The mass, lytic lesion of the skull, white matter lesion, diabetes insipidus, and cerebellar ataxia all suggested a final diagnosis of Langerhans cell histiocytosis (LCH), which was confirmed histopathologically.
27445532
(4904552)
 MALE Young Adult
Pulmonary Langerhans Cell Histiocytosis and Diabetes Insipidus in a Young Smoker.
Earlam K, Souza CA, Glikstein R, Gomes MM, Pakhale S.
Can Respir J. 2016;2016:3740902.
Pulmonary Langerhans Cell Histiocytosis and Diabetes Insipidus in a Young Smoker.
26508947
(4620353)
 OTHER
Pulmonary Langerhans Cell Histiocytosis in an Adult Male Presenting with Central Diabetes Insipidus and Diabetes Mellitus: A Case Report.
Choi YS, Lim JS, Kwon W, Jung SH, Park IH, Lee MK, Lee WY, Yong SJ, Lee SJ, Jung YR, Choi J, Choi JS, Jeong JT, Yoo JS, Kim SH.
Tuberc Respir Dis (Seoul). 2015;78(4):463-8.
Here, we report an uncommon case of pulmonary Langerhans cell histiocytosis that simultaneously presented with diabetes insipidus and diabetes mellitus.
24519262
 FEMALE Adult
Pulmonary Langerhans cell histiocytosis and diabetes insipidus in pregnant women: our experience.
Fuks L, Kramer MR, Shitrit D, Raviv Y.
Lung. 2014;192(2):285-7.
Pulmonary Langerhans cell histiocytosis and diabetes insipidus in pregnant women: our experience.
23275040
 MALE
A case of thymic Langerhans cell histiocytosis with diabetes insipidus as the first presentation.
Chen X, Huang X, Qiu Y, Chen H, Fu Y, Li X.
Front Med. 2013;7(1):143-6.
A case of thymic Langerhans cell histiocytosis with diabetes insipidus as the first presentation.
23538895
 FEMALE Young Adult
Histiocytosis X revealed by diabetes insipidus and skin lesions.
El Fekih N, Kamoun I, Jones M, Remmeh S, Zeglaoui F, Ben Slama C, Fazaa B.
Am J Dermatopathol. 2013;35(5):606-8.
Here we report an adult case where Langerhans cell histiocytosis presented with diabetes insipidus and cutaneous ulcers.
23848290
 MALE Child
Isolated tumorous Langerhans cell histiocytosis of the brainstem: a diagnostic and therapeutic challenge.
Savardekar A, Tripathi M, Bansal D, Vaiphei K, Gupta SK.
J Neurosurg Pediatr. 2013;12(3):258-61.
Langerhans cell histiocytosis (LCH) of the CNS is a rare entity, known to involve primarily the hypothalamicpituitary region, with the clinical hallmark of diabetes insipidus.
22729324
 FEMALE
Genital ulceration in a 4 year old--a case of safeguarding? From social services to pathology...
Roche E, Pandya N, Munthali L, Atra A.
BMJ Case Rep. 2012;2012:.
Furthermore, the complication of diabetes insipidus later developed, making this the youngest child described to our knowledge with vulval lesions of langerhans cell histiocytosis and a central nervous system complication.
22145482
 MALE
From idiopathic diabetes insipidus to neurodegenerative Langerhans cell histiocytosis--an unusual presentation and progression of disease.
Hayward RM, Nicolin G, Kennedy C, Joy H, Davies JH.
J Pediatr Endocrinol Metab. 2011;24(9-10):811-4.
From idiopathic diabetes insipidus to neurodegenerative Langerhans cell histiocytosis--an unusual presentation and progression of disease.
22145482
 MALE
From idiopathic diabetes insipidus to neurodegenerative Langerhans cell histiocytosis--an unusual presentation and progression of disease.
Hayward RM, Nicolin G, Kennedy C, Joy H, Davies JH.
J Pediatr Endocrinol Metab. 2011;24(9-10):811-4.
Diabetes insipidus (DI) is rare in childhood and has a wide-ranging aetiology including the involvement of uncontrolled proliferation of dendritic cells in the hypothalamic-pituitary axis, characteristic of Langerhans cell histiocytosis (LCH).
20420085
 FEMALE Adult
Langerhans cell histiocytosis: bilateral temporal bone involvement in an adult with diabetes insipidus.
Modugno GC, Brandolini C, Magnani G, Ferri GG, Sabattini E, Pirodda A.
B-ENT. 2010;6(1):67-72.
To present a clinical case of an adult affected by Langerhans cell histiocytosis with bilateral, non-simultaneous, involvement of the temporal bone, associated with diabetes insipidus and to review the literature.
20420085
 FEMALE Adult
Langerhans cell histiocytosis: bilateral temporal bone involvement in an adult with diabetes insipidus.
Modugno GC, Brandolini C, Magnani G, Ferri GG, Sabattini E, Pirodda A.
B-ENT. 2010;6(1):67-72.
Langerhans cell histiocytosis: bilateral temporal bone involvement in an adult with diabetes insipidus.
20420085
 FEMALE Adult
Langerhans cell histiocytosis: bilateral temporal bone involvement in an adult with diabetes insipidus.
Modugno GC, Brandolini C, Magnani G, Ferri GG, Sabattini E, Pirodda A.
B-ENT. 2010;6(1):67-72.
A rare case of bilateral temporal bone involvement of Langerhans cell histiocytosis in a 42-year-old woman affected by diabetes insipidus is reported.
20329585
 MALE Adult
[Central diabetes insipidus in adult patients--the first sign of Langerhans cell histiocytosis and Erdheim-Chester disease. Three case studies and literature review].
Adam Z, Balsikova K, Krejci M, Pour L, Stepankova S, Svacina P, Hermanova M, Vanicek J, Krupa P, Stanicek J, Koukalova R, Neubauer J, Krivanova A, Mayer J, Hajek R.
Vnitr Lek. 2010;56(2):138-48.
Diabetes insipidus was the first sign of Langerhans cell histiocytosis in 2 patients, and it was the first sign of Erdheim-Chester disease in one patient.
19076626
 FEMALE Adult
Clinical and immunohistochemical evaluation of the vulvar Langerhans cell histiocytosis.
Bongiorno MR, Pistone G, de Giorgi V, Arico M.
Dermatol Ther. 2008;21 Suppl 3:S15-20.
We present the case of a woman with diabetes insipidus with subsequent genital and multiorgan Langerhans cell histiocytosis (LCH).
18338395
 MIXED_SAMPLE Infant
Treatment of juvenile xanthogranuloma.
Stover DG, Alapati S, Regueira O, Turner C, Whitlock JA.
Pediatr Blood Cancer. 2008;51(1):130-3.
We report two cases of multisystem JXG presenting with clinical features more commonly seen in Langerhans cell histiocytosis (LCH), including diabetes insipidus and lytic bony lesions.
19097362
 MALE Adult
[Pathogenetically complicated case of osteoporosis in a young man].
Zofkova I.
Cas Lek Cesk. 2008;147(11):574-8.
The aim of this case study is to demonstrate the complex pathogenesis of a severe osteoporosis in a 23-year-old heavy smoker with histiocytosis X, diabetes insipidus (DI), subclinical hypogonadism and low serum levels of IGF-I.
16456689
 MALE
Isolated Langerhans cell histiocytosis of the infundibulum presenting with fulminant diabetes insipidus.
Horn EM, Coons SW, Spetzler RF, Rekate HL.
Childs Nerv Syst. 2006;22(5):542-4.
Isolated Langerhans cell histiocytosis of the infundibulum presenting with fulminant diabetes insipidus.
16680234
 MALE Adult
Liver involvement in Langerhans' cell histiocytosis. Case report.
Dina I, Copaescu C, Herlea V, Wrba F, Iacobescu C.
J Gastrointestin Liver Dis. 2006;15(1):57-9.
We report a case of Langerhans'cell histiocytosis in a young patient with clinical signs of diabetes insipidus and hepatic involvement in whom the immunohistochemical analysis of the liver tissue led to the definitive diagnosis.