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Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a systemic disease associated with the proliferation and accumulation (usually in granulomas) of Langerhans cells in various tissues.

Glucose intolerance (GI) can be defined as dysglycemia that comprises both prediabetes and diabetes. It includes the conditions of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) and diabetes mellitus (DM).

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PMID (PMCID)
2180296	MALE	Middle Aged
	Reversible hepatomegaly and diabetes mellitus in an adult with disseminated histiocytosis X.
	Trochtenberg DS, Dessypris EN. Am J Med Sci. 1990;299(3):179-84.
	The medical literature is reviewed with an emphasis on disseminated histiocytosis X in adults and the mechanism of glucose intolerance in liver disease.