Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a systemic disease associated with the proliferation and accumulation (usually in granulomas) of Langerhans cells in various tissues.

Headache

Cephalgia, or pain sensed in various parts of the head, not confined to the area of distribution of any nerve.


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PMID (PMCID)
6335282
 MALE Adult
[Cerebral and pulmonary histiocytosis X. Neurologic manifestations disclosing a pseudotumoral formation on the floor of the 4th ventricle].
Allard P, Kermarec J, Goasguen J, Ferry M, de Muizon H, Girard P, Herning R.
Rev Pneumol Clin. 1984;40(5):305-9.
The authors report a case of histiocytosis X which presented with neurological manifestations in a 20 year old man: episodes of headache with vomiting, followed, three months later, by the development of paralysis of the right 6th and 7th cranial nerves associated with nystagmus.